Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4981471 | 0.88 | ALDH1A1 (0.64) | SSTR4ALDH1A1SSTR1KMT2ADRD4 | |
| SCHEMBL4979013 | 0.81 | ALDH1A1 (0.73) | SSTR4ALDH1A1SSTR1DRD4SIGMAR1 | |
| SCHEMBL5472065 | 0.81 | LMNA (0.60) | LMNAALDH1A1GAAFABP3FABP4 | |
| SCHEMBL4975779 | 0.80 | DRD4 (0.59) | SSTR4MAPTDRD4EPHX2 | |
| SCHEMBL4982031 | 0.80 | ALDH1A1 (0.50) | LMNASSTR4ALDH1A1SSTR1EPHX2 | |
| SCHEMBL4982989 | 0.79 | NPC1 (0.57) | SSTR4ALDH1A1GAASSTR1KMT2A | |
| SCHEMBL4979388 | 0.77 | P2RX7 (0.54) | SSTR4ALDH1A1SSTR1DRD4SIGMAR1 | |
| SCHEMBL4982809 | 0.76 | DRD4 (0.49) | SSTR4ALDH1A1SSTR1DRD4EPHX2 | |
| SCHEMBL14263103 | 0.76 | P2RX7 (0.56) | SSTR4ALDH1A1SSTR1MAPTDRD4 | |
| SCHEMBL14263114 | 0.76 | DRD4 (0.73) | GAAMAPTKMT2ADRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | US | disclosed |
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | US | disclosed |
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064706-A1 | Piperidine Derivatives as Histamine H3 Receptor Ligands | HRH3, HRH1, HRH4 | LMNA 4587/4885SSTR4 654/4885ALDH1A1 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.