Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458403 | 0.75 | TSHR (0.45) | MAPTMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL3735442 | 0.75 | MAPT (0.52) | MAPTHPGDMAPK1L3MBTL1KMT2A | |
| SCHEMBL4006188 | 0.74 | HTR1A (0.42) | MAPTHPGDMAPK1L3MBTL1KMT2A | |
| SCHEMBL6497375 | 0.73 | ALDH1A1 (0.43) | MAPTHPGDMAPK1L3MBTL1KDM4E | |
| SCHEMBL1751411 | 0.72 | MAPT (0.49) | MAPTHPGDMAPK1L3MBTL1KMT2A | |
| SCHEMBL12877931 | 0.72 | CYP2D6 (0.44) | MAPTL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL1750892 | 0.71 | MAPT (0.48) | MAPTHPGDMAPK1L3MBTL1KMT2A | |
| SCHEMBL3381282 | 0.70 | FAAH (0.43) | MAPK1KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL5795265 | 0.70 | MAPT (0.58) | MAPTHPGDMAPK1L3MBTL1KMT2A | |
| SCHEMBL12135760 | 0.70 | APP (0.45) | MAPTHPGDMAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994026-A2 | NEW AMINES | Actelion Pharmaceuticals Ltd. (CH) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007102127-A2 | NEW AMINES | ACTELION PHARMACEUTICALS LTD (CH) | 2007-09-13 | — | — | WO | disclosed |