SCHEMBL4982859

SCHEMBL4982859

CC(CON1C(C)(C)CCCC1(C)C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.38
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GFER P55789 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
AOC3 Q16853 2/20 0.35
TRPA1 O75762 2/20 0.34
RIPK1 Q13546 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7781984 0.82 OPRM1 (0.32)
SCHEMBL4986264 0.81 KMT2A (0.38) TAAR1KDM4EALDH1A1GFERL3MBTL1
SCHEMBL13199413 0.79 MEN1 (0.34) KDM4EALDH1A1
SCHEMBL14608833 0.76 KDM4E (0.45) TAAR1KDM4EALDH1A1GFERL3MBTL1
SCHEMBL682099 0.76 CYP2D6 (0.36) ALDH1A1
SCHEMBL2139487 0.73 ALDH1A1 (0.49) ALDH1A1
SCHEMBL18642996 0.73 OPRM1 (0.40) ALDH1A1
SCHEMBL14379762 0.73 OPRM1 (0.34) ALDH1A1TRPA1
SCHEMBL8439515 0.72 OPRM1 (0.35) ALDH1A1L3MBTL1
SCHEMBL4621770 0.71 DHFR (0.43) TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7388052-B2 Process for the preparation of block copolymers POLIMERI EUROPA S.P.A. (IT) 2008-06-17 US disclosed
EP-1519970-B1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS POLIMERI EUROPA SPA (IT) 2007-10-24 EP disclosed
US-20070219329-A1 polymerizing styrene using a nitroxy free radical catalyst, then adding methacrylonitrile; 2-methyl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)propionitrile catalyst; POLIMERI EUROPA S.P.A. (IT) 2007-09-20 US disclosed
EP-1519970-A1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS Polimeri Europa S.p.A. (IT) 2005-04-06 EP disclosed
WO-2004005361-A1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS POLIMERI EUROPA S.P.A. (IT) 2004-01-15 WO disclosed