Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987925 | 0.94 | HDAC6 (0.44) | HDAC6L3MBTL1AKR1C3NAMPTALDH1A1 | |
| SCHEMBL4985245 | 0.90 | LMNA (0.38) | AKR1C3NAMPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4980960 | 0.90 | SMN1; SMN2 (0.46) | AKR1C3ALDH1A1LMNASMN1; SMN2MMP2 | |
| SCHEMBL4983067 | 0.88 | PKM (0.43) | L3MBTL1ALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL4985224 | 0.88 | AKR1C3 (0.42) | HDAC6AKR1C3EPHX1EPHX2SCN9A | |
| SCHEMBL4987011 | 0.85 | PKM (0.46) | L3MBTL1ALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL4980434 | 0.85 | MMP1 (0.41) | L3MBTL1NAMPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4987057 | 0.84 | LMNA (0.44) | L3MBTL1AKR1C3LMNASMN1; SMN2GAA | |
| SCHEMBL4982841 | 0.84 | LMNA (0.39) | L3MBTL1AKR1C3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4983020 | 0.83 | MEN1 (0.47) | L3MBTL1AKR1C3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | RENOVIS, INC. | 2008-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | P2RX7, P2RX3, P2RX2 | HDAC6 2582/4885L3MBTL1 4476/4885AKR1C3 1419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.