Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 8/20 | 0.49 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4988583 | 0.85 | KDM4E (0.46) | MAPTKDM4E | |
| SCHEMBL4985530 | 0.83 | MAOB (0.48) | MAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL4988199 | 0.83 | KMT2A (0.46) | MAPTP4HTMKDM4EMAPK1L3MBTL1 | |
| SCHEMBL4988893 | 0.82 | LMNA (0.40) | — | |
| SCHEMBL4991276 | 0.82 | NPC1 (0.42) | MAPT | |
| SCHEMBL1017155 | 0.81 | P4HTM (0.59) | P4HTMP4HA1MIFKDM4EMAPK1 | |
| SCHEMBL4985300 | 0.80 | HCAR3 (0.45) | MAPTP4HTMP4HA1MIFKDM4E | |
| SCHEMBL5782817 | 0.79 | HDAC1 (0.55) | MAPTKDM4E | |
| SCHEMBL370722 | 0.78 | P4HTM (0.59) | MAPTP4HTMP4HA1MIFKDM4E | |
| SCHEMBL4990228 | 0.77 | MAPT (0.48) | MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| CN-101039934-A | 1, 5-diheterocyclic-1H-triazole derivatives | DAIICHI SEIYAKU CO (JP) | 2007-09-19 | — | — | CN | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| CN-1774435-A | 5-membered heterocyclic derivative | DAIICHI SEIYAKU CO (JP) | 2006-05-17 | — | — | CN | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | MAPT 4736/4885P4HTM 3370/4885P4HA1 518/4885 |
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | MAPT 4426/4885P4HTM 3302/4885P4HA1 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.