Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559464 | 0.99 | TSHR (0.60) | TSHRRECQLALDH1A1KDM4ECYP1A2 | |
| SCHEMBL6538501 | 0.94 | TSHR (0.61) | TSHRRECQLALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2555132 | 0.89 | ALDH1A1 (0.59) | TSHRRECQLALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7195953 | 0.85 | TSHR (0.63) | TSHRRECQLALDH1A1KDM4EMEN1 | |
| SCHEMBL7195903 | 0.85 | TSHR (0.63) | TSHRRECQLALDH1A1KDM4EMEN1 | |
| SCHEMBL2557379 | 0.84 | ALDH1A1 (0.59) | TSHRRECQLALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL14112030 | 0.83 | RECQL (0.77) | TSHRRECQLKDM4ECYP1A2HPGD | |
| SCHEMBL10599988 | 0.83 | RECQL (0.77) | TSHRRECQLKDM4ECYP1A2HPGD | |
| SCHEMBL6538870 | 0.83 | RAB9A (0.63) | ALDH1A1KDM4ECYP1A2CYP2D6HPGD | |
| SCHEMBL14407886 | 0.82 | MEN1 (0.64) | TSHRRECQLALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2008-08-28 | — | — | US | disclosed |
| US-7375251-B2 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1836155-A2 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | Wyeth, A Corporation of the State of Delaware (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006076350-A2 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | ADH1A, ADH1C, ADH5 | TSHR 3144/4885RECQL 4327/4885ALDH1A1 12/4885 |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | ADH1A, ADH1C, ADH5 | TSHR 3144/4885RECQL 4327/4885ALDH1A1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.