Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4988076 | 0.84 | KMT2A (0.49) | KMT2AL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL4985224 | 0.84 | AKR1C3 (0.42) | LIPEAKR1C3KMT2A | |
| SCHEMBL4985355 | 0.82 | EPHX2 (0.37) | AKR1C3C5AR1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4986044 | 0.82 | FAAH (0.39) | LIPE | |
| SCHEMBL4989343 | 0.81 | AKR1C3 (0.44) | KDM2BLIPEAKR1C3ALDH1A1SLC40A1 | |
| SCHEMBL4991171 | 0.80 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL4986273 | 0.80 | PKM (0.42) | AKR1C3KMT2AL3MBTL1 | |
| SCHEMBL4992135 | 0.80 | ATM (0.41) | KDM2BL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL4989380 | 0.80 | ALDH1A1 (0.39) | KDM2BAKR1C3KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4988448 | 0.80 | MEN1 (0.45) | AKR1C3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | RENOVIS, INC. | 2008-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | P2RX7, P2RX3, P2RX2 | CHRM1 977/4885KDM2B 4316/4885LIPE 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.