Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436595 | 0.85 | MYC (0.41) | KMT2AALDH1A1KDM4ELMNATSHR | |
| SCHEMBL4987904 | 0.83 | CES2 (0.43) | KMT2AALDH1A1KDM4ECES2CES1 | |
| SCHEMBL4429455 | 0.81 | TSHR (0.44) | KMT2AALDH1A1KDM4ESLC6A3LMNA | |
| SCHEMBL4429636 | 0.80 | SLC6A4 (0.47) | KMT2AALDH1A1KDM4ESLC6A4SLC6A3 | |
| SCHEMBL20524639 | 0.79 | PTGS2 (0.51) | KMT2AALDH1A1KDM4ESLC6A4SLC6A3 | |
| SCHEMBL12890135 | 0.77 | ALDH1A1 (0.47) | KMT2AALDH1A1KDM4ELMNATSHR | |
| SCHEMBL4993080 | 0.77 | ALDH1A1 (0.41) | KMT2AALDH1A1KDM4ESLC6A4SLC6A3 | |
| SCHEMBL4995080 | 0.75 | KDM4E (0.41) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL4986578 | 0.74 | KDM4E (0.43) | ALDH1A1KDM4ECFTR | |
| SCHEMBL19511729 | 0.74 | MAPK1 (0.51) | ALDH1A1KDM4ESLC6A3LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | KMT2A 2978/4885ALDH1A1 1639/4885KDM4E 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.