Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 14/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966171 | 1.00 | FKBP1A (0.72) | FKBP1A | |
| SCHEMBL4675555 | 1.00 | FKBP1A (0.72) | FKBP1A | |
| Gpi-1485 SCHEMBL3568704 | 0.95 | FKBP1A (0.66) | FKBP1A | |
| Gpi-1485 SCHEMBL2006950 | 0.95 | FKBP1A (0.66) | FKBP1A | |
| Trifluoroacetic Acid SCHEMBL499188 | 0.93 | FKBP1A (0.64) | FKBP1A | |
| SCHEMBL6317432 | 0.89 | FKBP1A (0.57) | FKBP1A | |
| SCHEMBL7755136 | 0.88 | FKBP1A (0.58) | FKBP1A | |
| SCHEMBL4684233 | 0.88 | FKBP1A (0.69) | FKBP1A | |
| SCHEMBL4679982 | 0.88 | FKBP1A (0.69) | FKBP1A | |
| SCHEMBL5700567 | 0.88 | FKBP1A (0.69) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | The Government of the United States of America as represented (US) | 2008-04-10 | — | — | US | claimed |
| EP-1227859-B1 | NEUROPHILIN LIGANDS FOR TREATING OCULAR CONDITIONS | ALCON INC (CH) | 2006-08-09 | — | — | EP | claimed |
| JP-2002522485-A | — | — | 2002-07-23 | — | — | JP | claimed |
| US-6376517-B1 | FOR TREATING VISION LOSS, PREVENTING VISION DEGENERATION, AND PROMOTING VISION REGENERATION (?NEOPSIS?) | GPI NIL HOLDINGS, INC. | 2002-04-23 | — | — | US | claimed |
| EP-0777478-B1 | INHIBITORS OF ROTAMASE ENZYME ACTIVITY | GUILFORD PHARM INC (US) | 2001-11-07 | — | — | EP | claimed |
| US-20010036947-A1 | Pipecolic acid derivative hair growth compositions and uses | GPI NIL HOLDINGS, INC. (US) | 2001-11-01 | — | — | US | claimed |
| EP-1109554-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000009109-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| US-5843960-A | Inhibitors of rotamase enzyme activity | GPI NIL HOLDINGS, INC. (US) | 1998-12-01 | — | — | US | claimed |
| US-12594275-B2 | Immunophilin binding agents and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-04-07 | — | — | US | disclosed |
| US-12558356-B2 | Immunophilin binding agents and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250108052-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-04-03 | — | — | US | disclosed |
| EP-4242304-A2 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | Warp Drive Bio, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-4242304-A2 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | Warp Drive Bio, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| US-6133456-A | DIMERS OF THE MACROCYCLIC NATURAL PRODUCT, FK506, COVALENTLY ATTACHED TO EACH OTHER VIA A SYNTHETIC LINKER MOIETY | ARIAD GENE THERAPEUTICS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1011650-A1 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | Amgen Inc., (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-2000016603-A2 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL HOLDINGS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-2000009109-A2 | PIPECOLIC ACID DERIVATIVES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-1999014998-A2 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | AMGEN INC. (US) | 1999-04-01 | — | — | WO | disclosed |
| US-5786378-A | FKBP TYPE IMMUNOPHILLINS FOR NERVOUS SYSTEM DISORDERS | GPI NIL HOLDINGS, INC. (US) | 1998-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085238-A1 | Small Molecules for Imaging Protein-Protein Interactions | HSPBP1, HSPA2, HSPA8 | FKBP1A 1547/4885 |
| US-20010036947-A1 | Pipecolic acid derivative hair growth compositions and uses | PIP5K1C, PIP4K2C, PIP5K1A | FKBP1A 510/4885 |
| US-12594275-B2 | Immunophilin binding agents and uses thereof | CCR1, CCRL2, CCR3 | FKBP1A 1251/4885 |
| US-20250108052-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | SERPINA6, SELPLG, FABP7 | FKBP1A 376/4885 |
| US-12558356-B2 | Immunophilin binding agents and uses thereof | CCRL2, CFB, CCR3 | FKBP1A 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.