SCHEMBL4991475

SCHEMBL4991475

CCOC(=O)NNC(O)=S

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP2D6 P10635 1/20 0.41
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
SOAT1 P35610 1/20 0.37
EGLN1 Q9GZT9 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL355253 0.85 GAA (0.55) GAALMNASMN1; SMN2MGAMSI
SCHEMBL154280 0.83 GAA (0.53) GAALMNASMN1; SMN2MGAMSI
SCHEMBL3701771 0.82 LMNA (0.44) GAALMNASMN1; SMN2MGAMSI
SCHEMBL253171 0.80 ALOX15 (0.46) GAALMNASMN1; SMN2MGAMSI
SCHEMBL6967574 0.79
SCHEMBL8551216 0.78 LMNA (0.42) GAALMNASMN1; SMN2MGAMSI
SCHEMBL8585563 0.78 SMN1; SMN2 (0.42) GAALMNASMN1; SMN2MGAMSI
SCHEMBL11651480 0.78 LMNA (0.48) GAALMNASMN1; SMN2MGAMSI
SCHEMBL28604705 0.78 LMNA (0.48) GAALMNASMN1; SMN2MGAMSI
SCHEMBL32131 0.76 ALOX15 (0.52) GAALMNASMN1; SMN2MGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1119587-B1 PAVEMENT MARKING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2003-09-24 EP claimed
US-6521718-B2 Blend of acrylated resin and unsaturated monomer 3M INNOVATIVE PROPERTIES COMPANY 2003-02-18 US claimed
US-6350823-B1 ETHYLENIC UNSATURATED POLYMER, POLYUREA, POLYURETHANEUREAS AND POLYTHIOCARBAMATEUREAS WITH POLYCARBONATES, POLYETHERS OR POLYESTERS AND ETHYLENE 3M INNOVATIVE PROPERTIES COMPANY 2002-02-26 US claimed
US-20020016421-A1 Pavement marking composition 3M INNOVATIVE PROPERTIES COMPANY 2002-02-07 US claimed
EP-1119587-A1 PAVEMENT MARKING COMPOSITION 3M Innovative Properties Company (US) 2001-08-01 EP claimed
WO-2000020481-A1 PAVEMENT MARKING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-04-13 WO claimed
CN-101678620-B Thermoplastic polyurethane lenses with a specified weight percentage of urethane repeating units ESSILOR INT 2013-11-20 CN disclosed
CN-101678620-A Thermoplastic polyurethane lenses with urethane repeating units of specified weight percentage ESSILOR INT 2010-03-24 CN disclosed
US-20080097043-A1 Surface Support Method 3M INNOVATIVE PROPERTIES COMPANY 2008-04-24 US disclosed
EP-1791919-A1 SURFACE SUPPORT METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-06-06 EP disclosed
WO-2006034083-A1 SURFACE SUPPORT METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-03-30 WO disclosed
EP-1119587-B1 PAVEMENT MARKING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2003-09-24 EP disclosed
EP-1119587-B1 PAVEMENT MARKING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2003-09-24 EP disclosed
US-6350823-B1 ETHYLENIC UNSATURATED POLYMER, POLYUREA, POLYURETHANEUREAS AND POLYTHIOCARBAMATEUREAS WITH POLYCARBONATES, POLYETHERS OR POLYESTERS AND ETHYLENE 3M INNOVATIVE PROPERTIES COMPANY 2002-02-26 US disclosed
US-20020016421-A1 Pavement marking composition 3M INNOVATIVE PROPERTIES COMPANY 2002-02-07 US disclosed
US-20020016421-A1 Pavement marking composition 3M INNOVATIVE PROPERTIES COMPANY 2002-02-07 US disclosed
EP-1119587-A1 PAVEMENT MARKING COMPOSITION 3M Innovative Properties Company (US) 2001-08-01 EP disclosed
EP-1119587-A1 PAVEMENT MARKING COMPOSITION 3M Innovative Properties Company (US) 2001-08-01 EP disclosed
WO-2000020481-A1 PAVEMENT MARKING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-04-13 WO disclosed
WO-2000020481-A1 PAVEMENT MARKING COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-04-13 WO disclosed