Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585563 | 0.83 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2GAAALDH1A1MGAM | |
| SCHEMBL355253 | 0.82 | GAA (0.55) | LMNASMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL18591543 | 0.81 | MAPT (0.42) | LMNAGAAALDH1A1MGAMSI | |
| SCHEMBL9825086 | 0.78 | LMNA (0.44) | LMNASMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL3701771 | 0.78 | LMNA (0.44) | LMNASMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL4991475 | 0.78 | GAA (0.48) | LMNASMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL10837318 | 0.78 | GAA (0.50) | LMNAGAAALDH1A1CYP1A2TDP1 | |
| SCHEMBL253171 | 0.77 | ALOX15 (0.46) | LMNASMN1; SMN2GAAALDH1A1MGAM | |
| SCHEMBL154280 | 0.75 | GAA (0.53) | LMNASMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL4044207 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431291-B1 | Sulfonylaminocarbony-triazolinones having substituents attached through sulfur | BAYER AG (DE) | 1998-07-29 | — | — | EP | disclosed |
| US-5750718-A | CHEMICAL INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| US-5599944-A | Intermediates for herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| US-5380863-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| US-5276162-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| US-5149356-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |
| US-5085684-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| EP-0431291-A2 | Sulfonylaminocarbony-triazolinones having substituents attached through sulfur | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |