Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694297 | 0.85 | CA12 (0.48) | LMNAGAAMGAMSIMGAM2 | |
| SCHEMBL355253 | 0.85 | GAA (0.55) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL29047213 | 0.84 | GAA (0.44) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL3126038 | 0.82 | ALOX15 (0.48) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL4991475 | 0.82 | GAA (0.48) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL253171 | 0.80 | ALOX15 (0.46) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL4902117 | 0.79 | GAA (0.44) | LMNAGAAMGAMSIMGAM2 | |
| SCHEMBL8585563 | 0.78 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL8551216 | 0.78 | LMNA (0.42) | LMNASMN1; SMN2GAAMGAMSI | |
| SCHEMBL154280 | 0.78 | GAA (0.53) | LMNASMN1; SMN2GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013410-B1 | PROCESS FOR PREPARING OPTICAL THERMOPLASTIC URETHANE RESIN LENSES | ASAHI LITE OPTICAL CO LTD (JP) | 2005-11-16 | — | — | EP | claimed |
| CN-1175964-A | Optical thermoplastic copolymer and method for producing same | WASHI KOSAN KK (JP) | 1998-03-11 | — | — | CN | claimed |
| US-5679756-A | REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES | OPTIMA INC. (US) | 1997-10-21 | — | — | US | claimed |
| US-10150833-B2 | Polymer with urethane or thiourethane units for use, in particular, as an adhesion primer for bonding metal to rubber | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2018-12-11 | — | — | US | disclosed |
| EP-2989141-B1 | POLYMERS HAVING URETHANE OR THIOURETHANE UNITS, PARTICULARLY USABLE AS ADHESIVE PRIMER FOR ADHERING METAL TO RUBBER | MICHELIN & CIE (FR) | 2018-11-07 | — | — | EP | disclosed |
| US-20180280568-A1 | POLY(THIOKETAL URETHANE) SCAFFOLDS AND METHODS OF USE | VANDERBILT UNIVERSITY | 2018-10-04 | — | — | US | disclosed |
| EP-3362107-A1 | POLY(THIOKETAL-URETHANE) SCAFFOLDS AND METHODS OF USE | Vanderbilt University (US) | 2018-08-22 | — | — | EP | disclosed |
| US-20170119924-A1 | POLY(THIOKETAL-URETHANE) SCAFFOLDS AND METHODS OF USE | VANDERBILT UNIVERSITY | 2017-05-04 | — | — | US | disclosed |
| WO-2017066670-A1 | POLY(THIOKETAL-URETHANE) SCAFFOLDS AND METHODS OF USE | VANDERBILT UNIVERSITY (US) | 2017-04-20 | — | — | WO | disclosed |
| US-9463261-B2 | Poly(thioketal-urethane) scaffolds and methods of use | VANDERBILT UNIVERSITY (US) | 2016-10-11 | — | — | US | disclosed |
| US-20160122460-A1 | POLYMER WITH URETHANE OR THIOURETHANE UNITS FOR USE, IN PARTICULAR, AS AN ADHESION PRIMER FOR BONDING METAL TO RUBBER | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2016-05-05 | — | — | US | disclosed |
| WO-1999038673-A1 | EXTRUSION-COMPRESSION MOLDING OF OPTICAL ARTICLES | OPTIMA INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| CN-1175964-A | Optical thermoplastic copolymer and method for producing same | WASHI KOSAN KK (JP) | 1998-03-11 | — | — | CN | disclosed |
| CN-1175964-A | Optical thermoplastic copolymer and method for producing same | WASHI KOSAN KK (JP) | 1998-03-11 | — | — | CN | disclosed |
| US-5679756-A | REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES | OPTIMA INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5679756-A | REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES | OPTIMA INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5679756-A | REACTING POLYISOCYANATE WITH MONOMER HAVING AT LEAST TWO GROUPS REACTIVE WITH THE ISOCYANATES; OPHTHALMIC LENSES | OPTIMA INC. (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0780413-A1 | Optical thermoplastic thiourethane-urethane copolymers | Optima Inc. (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0780413-A1 | Optical thermoplastic thiourethane-urethane copolymers | Optima Inc. (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0780413-A1 | Optical thermoplastic thiourethane-urethane copolymers | Optima Inc. (US) | 1997-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119924-A1 | POLY(THIOKETAL-URETHANE) SCAFFOLDS AND METHODS OF USE | GRHPR, TKT, GLO1 | LMNA 2414/4885SMN1; SMN2 4539/4885GAA 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.