Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18764698 | 0.79 | ALDH1A1 (0.41) | TRPM8FFAR2LMNAGAATSHR | |
| SCHEMBL4994205 | 0.77 | GAA (0.40) | TRPM8FFAR2LMNAGAATSHR | |
| SCHEMBL4536011 | 0.76 | GAA (0.39) | TRPM8FFAR2LMNAGAATSHR | |
| SCHEMBL4539692 | 0.76 | TRPM8 (0.40) | TRPM8FFAR2LMNAGAATSHR | |
| SCHEMBL16180417 | 0.74 | LMNA (0.43) | TRPM8FFAR2LMNATSHRALDH1A1 | |
| SCHEMBL9834300 | 0.74 | ALDH1A1 (0.42) | TRPM8FFAR2LMNATSHRALDH1A1 | |
| SCHEMBL27872472 | 0.72 | GRIK1 (0.40) | TRPM8FFAR2LMNAGAATSHR | |
| SCHEMBL17397408 | 0.72 | TRPM8 (0.38) | TRPM8FFAR2LMNAGAATSHR | |
| SCHEMBL27872471 | 0.72 | GRIK1 (0.40) | TRPM8FFAR2LMNAGAATSHR | |
| SCHEMBL2936251 | 0.71 | FFAR2 (0.49) | TRPM8FFAR2LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419961-B2 | 9a-azalides with anti-inflammatory activity | ZAMBON S.P.A. (IT) | 2008-09-02 | — | — | US | disclosed |
| US-20060166904-A1 | 9a-azalides with anti-inflammatory activity | ZAMBON GROUP S.P.A. (IT) | 2006-07-27 | — | — | US | disclosed |
| EP-1556397-B1 | 9A-AZALIDES WITH ANTI-INFLAMMATORY ACTIVITY | ZAMBON SPA (IT) | 2006-03-08 | — | — | EP | disclosed |
| EP-1556397-A1 | 9A-AZALIDES WITH ANTI-INFLAMMATORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039821-A1 | 9A-AZALIDES WITH ANTI-INFLAMMATORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166904-A1 | 9a-azalides with anti-inflammatory activity | MPO, PDE9A, DPP9 | TRPM8 2918/4885FFAR2 1648/4885LMNA 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.