Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14030608 | 0.83 | ADRB2 (0.65) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL11021761 | 0.80 | ADRB2 (0.45) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL29751132 | 0.78 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL461364 | 0.78 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL19422886 | 0.78 | ADRB2 (0.48) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL5008664 | 0.78 | ADRB2 (0.60) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL9864677 | 0.76 | ADRB2 (0.67) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10697205 | 0.76 | ADRB2 (0.64) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10477749 | 0.76 | ADRB2 (0.46) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10464526 | 0.75 | ADRB2 (0.50) | ADRB2ADRB1ADRB3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937626-B1 | Process and intermediates for the preparation of Salmeterol | GENERICS UK LTD (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-8648214-B2 | Processes suitable for the preparation of salmeterol | GENERICS [UK] LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| EP-2641893-A1 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS SALTS | Generics [UK] Limited (GB) | 2013-09-25 | — | — | EP | disclosed |
| US-20080262267-A1 | NOVEL PROCESS | GENERICS [UK] LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262267-A1 | NOVEL PROCESS | CYP4A11, HSD3B1, HSD11B1 | ADRB2 128/4885ADRB1 53/4885ADRB3 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.