Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898402 | 0.83 | CCR1 (0.58) | CYP11B1CYP11B2CYP19A1SLC40A1LMNA | |
| SCHEMBL5012780 | 0.82 | CYP1A2 (0.47) | CYP11B1CYP11B2CYP19A1SLC40A1KDM4E | |
| SCHEMBL38652754 | 0.82 | ACP1 (0.39) | LMNAKDM4EMAPTACP1POLB | |
| SCHEMBL18796126 | 0.76 | RIPK1 (0.47) | CYP11B1CYP11B2LMNAMAPTPOLB | |
| SCHEMBL13302131 | 0.75 | RAB9A (0.55) | CYP11B1CYP11B2CYP19A1LMNAKDM4E | |
| SCHEMBL10077023 | 0.75 | PARP1 (0.49) | LMNAACP1ALDH1A1CCR1CCR5 | |
| SCHEMBL169529 | 0.74 | MAPT (0.47) | CYP11B1CYP11B2CYP19A1LMNAKDM4E | |
| SCHEMBL826938 | 0.74 | ALDH1A1 (0.55) | CYP11B1CYP11B2CYP19A1LMNAKDM4E | |
| Ether SCHEMBL16334360 | 0.74 | ALDH1A1 (0.41) | SLC40A1LMNAKDM4EMAPTPDE5A | |
| SCHEMBL14686182 | 0.73 | ACP1 (0.43) | LMNAKDM4EMAPTACP1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462600-B2 | Macrolides | PFIZER INC (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060135447-A1 | Macrolides | CHUPAK LOUIS S | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135447-A1 | Macrolides | LCAT, NOP2, HDAC6 | CYP11B1 608/4885CYP11B2 375/4885CYP19A1 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.