Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010114 | 0.89 | MAPT (0.49) | S100BMAPTGAAHTTPKM | |
| SCHEMBL81552 | 0.83 | S100B (0.53) | S100BMAPTGAAHTTPKM | |
| SCHEMBL5667453 | 0.83 | CNR2 (0.42) | S100BMAPTGAAHTTALDH1A1 | |
| SCHEMBL237533 | 0.81 | S100B (0.45) | S100BMAPTGAAHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL237232 | 0.80 | S100B (0.50) | S100BMAPTGAAHTTPKM | |
| SCHEMBL80268 | 0.80 | MAPT (0.58) | S100BMAPTGAAHTTPKM | |
| Oxalic Acid SCHEMBL238206 | 0.78 | S100B (0.45) | S100BMAPTHTTALDH1A1CYP3A4 | |
| SCHEMBL5554796 | 0.78 | MEN1 (0.40) | S100BMAPTGAAHTTPKM | |
| SCHEMBL5670995 | 0.77 | S100B (0.39) | S100BMAPTGAAHTTPKM | |
| SCHEMBL9748491 | 0.76 | ALDH1A1 (0.39) | MAPTHTTALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311524-A1 | Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor | AGFA GRAPHICS N.V. (BE) | 2008-12-18 | — | — | US | disclosed |