Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HEXA | P06865 | 1/20 | 0.34 |
| ▸ | HEXB | P07686 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008921 | 0.98 | TSHR (0.41) | TSHRALDH1A1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL5008803 | 0.86 | TSHR (0.36) | TSHRALDH1A1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL5012483 | 0.84 | TSHR (0.38) | TSHRALDH1A1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL369840 | 0.80 | TSHR (0.54) | TSHRALDH1A1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL5012502 | 0.79 | PTGS2 (0.38) | ALDH1A1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL6564122 | 0.76 | ACHE (0.60) | TSHRALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL1864858 | 0.74 | GRIN2D (0.43) | ALDH1A1SMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL8613228 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL1765158 | 0.74 | TSHR (0.67) | TSHRALDH1A1CYP1A2KDM4ECYP2C19 | |
| SCHEMBL30354037 | 0.74 | ACHE (0.64) | TSHRALDH1A1CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |