Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010583 | 0.80 | HTR2A (0.81) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5011454 | 0.78 | HTR2A (0.77) | HTR2AHTR2CSLC6A4TP53CNR2 | |
| SCHEMBL3851675 | 0.77 | TAS2R14 (0.51) | MAPTLMNAMEN1KMT2APSEN1 | |
| SCHEMBL5011732 | 0.77 | HTR2A (1.00) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5011430 | 0.76 | HTR2A (0.70) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5009433 | 0.75 | HTR2A (0.61) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL533000 | 0.75 | ACLY (0.68) | HTR2AHTR2CSLC6A4TP53LMNA | |
| SCHEMBL5010582 | 0.74 | CNR2 (0.71) | HTR2AHTR2CSLC6A4TP53CNR2 | |
| SCHEMBL5012972 | 0.74 | HTR2A (0.53) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5010683 | 0.73 | HTR2A (0.70) | HTR2AHTR2CSLC6A4TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | claimed |
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |