Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533000 | 0.78 | ACLY (0.68) | HTR2AHTR2CSLC6A4HTTTP53 | |
| SCHEMBL5010583 | 0.75 | HTR2A (0.81) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5010585 | 0.74 | HTR2A (0.62) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5009435 | 0.71 | ALDH1A1 (0.56) | HTR2AHTR2CSLC6A4HTTMAPT | |
| SCHEMBL5011454 | 0.70 | HTR2A (0.77) | HTR2AHTR2CSLC6A4TP53CNR2 | |
| SCHEMBL1170152 | 0.70 | TAS2R14 (0.49) | HTTTP53MAPTLMNAPKM | |
| SCHEMBL6751428 | 0.69 | HTR2A (0.59) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5011732 | 0.69 | HTR2A (1.00) | HTR2AHTR2CSLC6A4TP53MAPT | |
| SCHEMBL5010707 | 0.69 | HSD11B1 (0.60) | HTR2AHTR2CSLC6A4HTTTP53 | |
| SCHEMBL16210929 | 0.69 | L3MBTL1 (0.58) | HTTTP53MAPTLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |