SCHEMBL501069

SCHEMBL501069

CC(C)(C)OC(=O)NCCOS(C)(=O)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.50
CA2 P00918 10/20 0.50
CA12 O43570 9/20 0.50
CA9 Q16790 7/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
IDO1 P14902 1/20 0.43
EPHX1 P07099 1/20 0.42
MALT1 Q9UDY8 1/20 0.40
CA14 Q9ULX7 2/20 0.39
CA7 P43166 1/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1811776 0.94 TDP1 (0.53) CA1CA2CA12CA9TDP1
SCHEMBL30596166 0.94 CA12 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL14740858 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL14745412 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL31395837 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL499627 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL15969366 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL21070189 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL21070363 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1
SCHEMBL14744716 0.90 CA1 (0.46) CA1CA2CA12CA9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085058-A1 DEGRADERS OF SON OF SEVENLESS HOMOLOG 1 YUAN YU (US) 2026-03-26 US disclosed
US-20250154141-A1 BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-05-15 US disclosed
CN-119954715-A Preparation method of doxylamine succinate 金陵药业股份有限公司 2025-05-09 CN disclosed
EP-3976617-B1 FUSED HETEROCYCLIC DERIVATIVES JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2025-04-23 EP disclosed
US-20250051347-A1 BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER Hinova Pharmaceuticals, Inc. (CN) 2025-02-13 US disclosed
US-12162882-B2 Quinolone derivatives as fibroblast growth factor receptor inhibitors PRINCIPIA BIOPHARMAC, INC. (US) 2024-12-10 US disclosed
US-20240391948-A1 NOVEL COMPOUND THAT INHIBITS TNF-ALPHA GENERATION AND INFLAMMASOME ACTIVITY AND PREPARATION METHOD THEREFOR SHAPERON INC. (KR) 2024-11-28 US disclosed
EP-3885340-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2024-11-27 EP disclosed
US-20240383886-A1 Protein Tyrosine Phosphatase Degraders and Methods of Use Thereof ABBVIE INC. 2024-11-21 US disclosed
CN-116162071-B Lipid compound, composition containing lipid compound, preparation method and application of lipid compound 尧唐(上海)生物科技有限公司 2024-10-22 CN disclosed
US-6528525-B1 Amidocarboxylic acid derivatives SANKYO COMPANY, LIMITED (JP) 2003-03-04 US disclosed
EP-1241170-A2 Pyrazolopyrimidine derivatives Pfizer Limited (GB) 2002-09-18 EP disclosed
US-20010053779-A1 Novel compounds and compositions for treating diseases asociated with protease activity Celera Corporation 2001-12-20 US disclosed
CN-1280561-A Amidocarboxylic acid derivatives SANKYO CO (JP) 2001-01-17 CN disclosed
EP-1026149-A1 AMIDOCARBOXYLIC ACID DERIVATIVES Sankyo Company Limited (JP) 2000-08-09 EP disclosed
EP-1019382-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH SERINE PROTEASE, PARTICULARLY TRYPTASE, ACTIVITY AXYS PHARMACEUTICALS, INC. (US) 2000-07-19 EP disclosed
WO-1998045275-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH SERINE PROTEASE, PARTICULARLY TRYPTASE, ACTIVITY AXYS PHARMACEUTICALS CORPORATION (US) 1998-10-15 WO disclosed
US-5710159-A IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1998-01-20 US disclosed
EP-0620824-A1 PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-10-26 EP disclosed
WO-1993014113-A1 PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154141-A1 BCL-XL/BCL-2 DUAL DEGRADERS FOR TREATMENT OF CANCERS BCL2, BCL2L2, BCL2L1 CA1 3545/4885CA2 2901/4885CA12 3366/4885
US-12162882-B2 Quinolone derivatives as fibroblast growth factor receptor inhibitors FGFR1, FGFR3, FGFR2 CA1 4828/4885CA2 4084/4885CA12 4848/4885
US-20240383886-A1 Protein Tyrosine Phosphatase Degraders and Methods of Use Thereof PTPN5, PTPN1, PTPN2 CA1 4518/4885CA2 3730/4885CA12 4295/4885
US-20240391948-A1 NOVEL COMPOUND THAT INHIBITS TNF-ALPHA GENERATION AND INFLAMMASOME ACTIVITY AND PREPARATION METHOD THEREFOR TNF, IL1B, IL1A CA1 4643/4885CA2 4749/4885CA12 4879/4885
US-20010053779-A1 Novel compounds and compositions for treating diseases asociated with protease activity CMA1, CPA3, TPSG1 CA1 377/4885CA2 395/4885CA12 546/4885
US-20250051347-A1 BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER AR, ADRM1, MDM2 CA1 1237/4885CA2 3525/4885CA12 1736/4885
US-20260085058-A1 DEGRADERS OF SON OF SEVENLESS HOMOLOG 1 SOS1, KRAS, SOS2 CA1 2798/4885CA2 2906/4885CA12 2738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.