Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010726 | 0.94 | MAPT (0.46) | MAPTSMN1; SMN2NPSR1NTSR1FBP1 | |
| SCHEMBL1856660 | 0.90 | PTGS2 (0.43) | MAPTSMN1; SMN2NPSR1NTSR1FBP1 | |
| SCHEMBL4000084 | 0.82 | MEN1 (0.38) | MAPTNPSR1LMNAALDH1A1MEN1 | |
| SCHEMBL2411848 | 0.79 | KMT2A (0.59) | MAPTSMN1; SMN2NPSR1PTGS2LMNA | |
| SCHEMBL12663967 | 0.78 | MEN1 (0.56) | MAPTNPSR1LMNAGRIK1GRIK2 | |
| SCHEMBL12663975 | 0.78 | MEN1 (0.56) | MAPTNPSR1LMNAGRIK1GRIK2 | |
| SCHEMBL1856375 | 0.78 | FBP1 (0.58) | MAPTSMN1; SMN2FBP1PTGS2KDM4E | |
| SCHEMBL11779893 | 0.76 | GLO1 (0.58) | FBP1LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL9476058 | 0.75 | GLO1 (0.56) | MAPTSMN1; SMN2FBP1KDM4EMAOB | |
| SCHEMBL8556148 | 0.75 | GLO1 (0.56) | MAPTSMN1; SMN2FBP1KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012373-A1 | S-TRIAZINE SUNSCREENS BEARING HINDERED PARA-AMINOBENZALMALONATE/PARA-AMINOBENZALMALONAMIDE AND AMINOBENZOATE/AMINOBENZAMIDE SUBSTITUENTS | L'OREAL (FR) | 2013-01-10 | — | — | US | disclosed |
| US-8323624-B2 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | L'OREAL (FR) | 2012-12-04 | — | — | US | disclosed |
| US-20080008669-A1 | Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds | L'OREAL (FR) | 2008-01-10 | — | — | US | disclosed |
| US-20070218022-A1 | Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds | L'OREAL, PARIS, FRANCE | 2007-09-20 | — | — | US | disclosed |
| US-20070196294-A1 | Photostable sunscreen compositions comprising dibenzoylmethane compound UV-A filters and s-triazine compounds | L'OREAL (FR) | 2007-08-23 | — | — | US | disclosed |
| US-7217821-B2 | Photoprotective cosmetic compositions comprising para-aminobenzalmalonate-substituted s-triazine compounds | L'OREAL (FR) | 2007-05-15 | — | — | US | disclosed |
| US-20060045859-A1 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | L'OREAL (FR) | 2006-03-02 | — | — | US | disclosed |
| US-20040234464-A1 | Photoprotective cosmetic compositions comprising para-aminobenzalmalonate-substituted s-triazine compounds | L'OREAL (FR) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070218022-A1 | Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds | NISCH, SUN2, CDC73 | MAPT 1002/4885SMN1; SMN2 4048/4885NPSR1 2993/4885 |
| US-20060045859-A1 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | TYR, ARSA, TST | MAPT 878/4885SMN1; SMN2 4437/4885NPSR1 2995/4885 |
| US-20130012373-A1 | S-TRIAZINE SUNSCREENS BEARING HINDERED PARA-AMINOBENZALMALONATE/PARA-AMINOBENZALMALONAMIDE AND AMINOBENZOATE/AMINOBENZAMIDE SUBSTITUENTS | TYR, ARSA, TST | MAPT 878/4885SMN1; SMN2 4437/4885NPSR1 2995/4885 |
| US-20080008669-A1 | Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds | NISCH, SUN2, ERCC5 | MAPT 724/4885SMN1; SMN2 3917/4885NPSR1 3035/4885 |
| US-20070196294-A1 | Photostable sunscreen compositions comprising dibenzoylmethane compound UV-A filters and s-triazine compounds | SUN2, ERCC5, NISCH | MAPT 263/4885SMN1; SMN2 4202/4885NPSR1 3968/4885 |
| US-20040234464-A1 | Photoprotective cosmetic compositions comprising para-aminobenzalmalonate-substituted s-triazine compounds | TYR, MSH6, ERCC5 | MAPT 1600/4885SMN1; SMN2 4434/4885NPSR1 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.