Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.50 |
| ▸ | IGF1R | P08069 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.50 |
| ▸ | LYN | P07948 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.50 |
| ▸ | MARK3 | P27448 | 2/20 | 0.50 |
| ▸ | BLK | P51451 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.50 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.50 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167891 | 0.84 | MAP3K5 (0.60) | CDK2CDK1GSK3BIGF1RJAK2 | |
| SCHEMBL31381352 | 0.84 | MAP3K5 (0.60) | CDK2CDK1GSK3BIGF1RJAK2 | |
| SCHEMBL27770482 | 0.84 | MAP3K5 (0.60) | CDK2CDK1GSK3BIGF1RJAK2 | |
| Benzene SCHEMBL28188863 | 0.84 | MAP3K5 (0.60) | CDK2CDK1GSK3BIGF1RJAK2 | |
| Hydrochloric Acid SCHEMBL8807679 | 0.82 | MAP3K5 (0.58) | CDK2CDK1GSK3BIGF1RJAK2 | |
| SCHEMBL4573935 | 0.82 | MAP3K5 (0.58) | CDK2CDK1GSK3BIGF1RJAK2 | |
| SCHEMBL7757002 | 0.80 | PDGFRB (0.59) | CDK2CDK1AURKAKDRLCK | |
| SCHEMBL25053109 | 0.79 | CDK4 (0.52) | CDK2CDK1GSK3BIGF1RJAK2 | |
| SCHEMBL14724701 | 0.79 | CDK1 (0.52) | CDK2CDK1GSK3BIGF1RJAK2 | |
| SCHEMBL24151364 | 0.79 | ADRB2 (0.55) | CDK2CDK1GSK3BIGF1RJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171874-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | WYETH (US) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171874-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | PDXK, PKD1, GLS | CDK2 304/4885CDK1 324/4885GSK3B 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.