Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.46 |
| ▸ | BAD | Q92934 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011002 | 0.86 | PDCD1 (0.43) | CHRNB2CHRNA4MCL1BADL3MBTL1 | |
| SCHEMBL5013873 | 0.79 | TDP1 (0.58) | TDP1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL5008840 | 0.78 | HNF4A (0.44) | CHRNB2CHRNA4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5010021 | 0.76 | MAPT (0.49) | CHRNB2CHRNA4TDP1MCL1L3MBTL1 | |
| SCHEMBL5008902 | 0.73 | HNF4A (0.43) | CHRNB2CHRNA4L3MBTL1MEN1KMT2A | |
| SCHEMBL5010784 | 0.73 | TDP1 (0.56) | TDP1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL17435206 | 0.73 | TDP1 (0.70) | TDP1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5008897 | 0.73 | HNF4A (0.46) | CHRNB2CHRNA4L3MBTL1MEN1KMT2A | |
| SCHEMBL7274909 | 0.72 | CHRNB2 (0.51) | CHRNB2CHRNA4TDP1MCL1BAD | |
| SCHEMBL5011024 | 0.72 | TDP1 (0.63) | TDP1L3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |