Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011613 | 0.80 | APP (0.56) | RORCAPP | |
| SCHEMBL5011741 | 0.77 | APP (0.55) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4496621 | 0.76 | DGAT1 (0.43) | DGAT1SOAT1PSEN1PSEN2APH1B | |
| SCHEMBL1115081 | 0.71 | CA2 (0.52) | CA2 | |
| SCHEMBL29718749 | 0.71 | CA2 (0.52) | CA2 | |
| SCHEMBL5011588 | 0.71 | APP (0.45) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29580771 | 0.71 | ALDH1A1 (0.57) | CA2 | |
| SCHEMBL27776461 | 0.71 | KIF11 (0.50) | CA2 | |
| SCHEMBL5009692 | 0.69 | APP (0.56) | RORCPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31481107 | 0.69 | CA2 (0.42) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893562-A1 | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B | Merck Frosst Canada Ltd. (CA) | 2008-03-05 | — | — | EP | claimed |
| WO-2006133559-A1 | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B | MERCK FROSST CANADA LTD. (CA) | 2006-12-21 | — | — | WO | claimed |