SCHEMBL5011883

SCHEMBL5011883

CCCCCCCc1c2nc(c(-c3c(Br)cccc3Br)c3ccc([nH]3)c(CCCCCCC)c3nc(c(-c4c(Br)cccc4Br)c4ccc1[nH]4)C=C3)C=C2

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 3/20 0.37
▸ KCNH2 Q12809 1/20 0.37
▸ SLC2A1 P11166 1/20 0.33
▸ GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15468129 0.84 KCNH2 (0.42) TERTKCNH2GPR84
SCHEMBL9438134 0.84 KCNH2 (0.42) TERTKCNH2GPR84
SCHEMBL433614 0.84 KCNH2 (0.42) TERTKCNH2GPR84
SCHEMBL8601755 0.84 KCNH2 (0.42) TERTKCNH2GPR84
SCHEMBL1194293 0.83 KCNH2 (0.39) TERTKCNH2
SCHEMBL17419216 0.82 KCNH2 (0.36) TERTKCNH2SLC2A1GPR84
SCHEMBL9231247 0.81 TERT (0.48) TERT
SCHEMBL7262879 0.80 TERT (0.34) TERTKCNH2
SCHEMBL2316794 0.79 GCGR (0.50) TERT
SCHEMBL2337728 0.79 GCGR (0.50) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 — — US disclosed
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 — — US disclosed
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 — — US disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 — — US disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG TERT 645/4885KCNH2 1472/4885SLC2A1 4731/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS TERT 1385/4885KCNH2 4163/4885SLC2A1 4722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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