Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468129 | 1.00 | KCNH2 (0.42) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8601755 | 1.00 | KCNH2 (0.42) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9438134 | 1.00 | KCNH2 (0.42) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL1194293 | 0.98 | KCNH2 (0.39) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL3475623 | 0.93 | MAPT (0.41) | HSD17B10KDM4EALDH1A1HPGDTERT | |
| SCHEMBL17419216 | 0.91 | KCNH2 (0.36) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6003452 | 0.91 | KCNH2 (0.36) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6004323 | 0.90 | CCNB2 (0.35) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL7262879 | 0.89 | TERT (0.34) | KCNH2HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6003423 | 0.89 | TERT (0.34) | KCNH2HSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459955-B1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBERATUNGS II AG (AT) | 2022-11-02 | — | — | EP | disclosed |
| EP-3459955-A1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | biolitec Unternehmensbeteiligungs II AG (AT) | 2019-03-27 | — | — | EP | disclosed |
| EP-2350058-B1 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2018-10-24 | — | — | EP | disclosed |
| EP-2870159-B1 | APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2017-06-28 | — | — | EP | disclosed |
| CN-103097390-B | β functionalization dihydroxy chlorin is used for the application of PDT | 拜欧利泰克投资二代公司 | 2017-03-08 | — | — | CN | disclosed |
| US-9315510-B2 | Method and application of unsymmetrically meso-substituted porphyrins and chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2016-04-19 | — | — | US | disclosed |
| CN-102159569-B | The porphyrin replaced for the asymmetric meso of PDT and chlorin and application thereof | Beletech Pharmaceutical Market Co.,Ltd. (MY) | 2016-02-03 | — | — | CN | disclosed |
| US-9156849-B2 | Application of β-functionalized dihydroxy-chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2015-10-13 | — | — | US | disclosed |
| EP-2870159-A2 | APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2015-05-13 | — | — | EP | disclosed |
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. | 2013-02-14 | — | — | US | disclosed |
| WO-2012012809-A2 | APPLICATION OF β-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CERAMOPTEC GMBH (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-20110206613-A1 | METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2011-08-25 | — | — | US | disclosed |
| EP-2350058-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033678-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206613-A1 | METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | PTDSS2, PTDSS1, DLST | KCNH2 1786/4885HSD17B10 4149/4885KDM4E 2492/4885 |
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | TK1, DHPS, DLD | KCNH2 1082/4885HSD17B10 1776/4885KDM4E 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.