SCHEMBL5011931

SCHEMBL5011931

Brc1c2nc(c(-c3ccccc3)c3ccc(cc4nc(c(-c5ccccc5)c5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.74
▸ STAT1 P42224 1/20 0.74
▸ TOP1 P11387 4/20 0.43
▸ CYCS P99999 3/20 0.42
▸ TERT O14746 4/20 0.41
▸ ENPP2 Q13822 1/20 0.39
▸ ABCG2 Q9UNQ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2940532 1.00 STAT3 (0.74) STAT3STAT1TOP1CYCSTERT
SCHEMBL5134031 1.00 STAT3 (0.74) STAT3STAT1TOP1CYCSTERT
SCHEMBL30767176 1.00 STAT3 (0.74) STAT3STAT1TOP1CYCSTERT
SCHEMBL5134266 0.99 STAT3 (0.72) STAT3STAT1TOP1CYCSTERT
SCHEMBL5013665 0.96 STAT3 (0.71) STAT3STAT1TOP1CYCSTERT
SCHEMBL30293296 0.92 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL31550992 0.92 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL1224432 0.92 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL31324939 0.91 STAT3 (0.84) STAT3STAT1TOP1CYCSTERT
SCHEMBL31324940 0.91 STAT3 (0.84) STAT3STAT1TOP1CYCSTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110730782-B Photodynamic therapy compounds and photodynamic therapy methods 光盐生物科技有限公司 2024-01-02 — — CN disclosed
US-11147797-B2 Photodynamic therapeutic compounds and photodynamic methods of treatment SALT AND LIGHT PHARMACEUTICALS PTY. LTD. (AU) 2021-10-19 — — US disclosed
CN-110730782-A Photodynamic therapy compounds and methods of photodynamic therapy 光盐生物科技有限公司 2020-01-24 — — CN disclosed
WO-2018102849-A9 PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT SALT AND LIGHT PHARMACEUTICALS PTY. LTD. (AU) 2019-11-28 — — WO disclosed
US-20190307725-A1 PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT SALT AND LIGHT PHARMACEUTICALS PTY. LTD. (AU) 2019-10-10 — — US disclosed
EP-3548494-A1 PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT Salt and Light Pharmaceuticals Pty. Ltd. (AU) 2019-10-09 — — EP disclosed
EP-3005387-B1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL RICOH CO LTD (JP) 2019-04-03 — — EP disclosed
WO-2018102849-A1 PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT SALT AND LIGHT PHARMACEUTICALS PTY. LTD. (AU) 2018-06-14 — — WO disclosed
US-9640330-B2 Photoelectric conversion element and solar cell RICOH COMPANY, LTD. (JP) 2017-05-02 — — US disclosed
US-20160126021-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL RICOH COMPANY, LTD. (JP) 2016-05-05 — — US disclosed
EP-3005387-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL Ricoh Company, Ltd. (JP) 2016-04-13 — — EP disclosed
WO-2014196659-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL RICOH COMPANY, LTD. (JP) 2014-12-11 — — WO disclosed
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 — — US disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 — — US disclosed
US-6951935-B2 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-10-04 — — US disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG STAT3 3817/4885STAT1 4312/4885TOP1 1268/4885
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same PPOX, HMBS, UROD STAT3 4156/4885STAT1 3973/4885TOP1 3026/4885
US-20190307725-A1 PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT PPOX, QDPR, ALDH1A2 STAT3 115/4885STAT1 270/4885TOP1 1742/4885
US-11147797-B2 Photodynamic therapeutic compounds and photodynamic methods of treatment PPOX, QDPR, ALDH1A2 STAT3 115/4885STAT1 270/4885TOP1 1742/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS STAT3 2986/4885STAT1 3579/4885TOP1 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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