Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647493 | 0.84 | GPR119 (0.52) | SLC6A2SLC6A4EPHX2HRH3 | |
| SCHEMBL27662478 | 0.78 | SLC6A2 (0.49) | SLC6A2SLC6A4EPHX2HRH3KCNA5 | |
| SCHEMBL648828 | 0.78 | BCHE (0.51) | SLC6A2SLC6A4 | |
| SCHEMBL646801 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4MMP1MMP3MMP9 | |
| SCHEMBL3910930 | 0.73 | SLC6A4 (0.61) | SLC6A2SLC6A4EPHX2HRH3 | |
| SCHEMBL744515 | 0.72 | LIPE (0.64) | — | |
| SCHEMBL9104053 | 0.72 | KCNA5 (0.62) | EPHX2HRH3KCNA5 | |
| SCHEMBL4542679 | 0.71 | SLC6A4 (0.46) | SLC6A2SLC6A4EPHX2HSD11B1KMT2A | |
| SCHEMBL3953696 | 0.70 | SLC6A2 (0.51) | SLC6A2SLC6A4EPHX2 | |
| SCHEMBL5372796 | 0.70 | ALDH1A1 (0.52) | HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |