Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090670 | 0.85 | KCNN4 (0.43) | KCNN4CHRM4 | |
| SCHEMBL2094030 | 0.80 | SCN9A (0.42) | KCNN4 | |
| SCHEMBL5013395 | 0.76 | MEN1 (0.47) | DRD2DRD4KDM4EALDH1A1DRD3 | |
| SCHEMBL5016238 | 0.76 | DRD2 (0.41) | DRD2DRD4KDM4EALDH1A1DRD3 | |
| SCHEMBL5016095 | 0.75 | ALDH1A1 (0.43) | DRD2DRD4KDM4EALDH1A1GAA | |
| SCHEMBL5536602 | 0.73 | DRD2 (0.54) | DRD2DRD4DRD1KDM4EALDH1A1 | |
| SCHEMBL27665953 | 0.73 | KDM4E (0.52) | KCNN4DRD2DRD4KDM4EALDH1A1 | |
| SCHEMBL5013364 | 0.72 | TSHR (0.50) | DRD2DRD4ALDH1A1DRD3GPR6 | |
| SCHEMBL27644470 | 0.71 | DRD2 (0.43) | DRD2DRD4KDM4EALDH1A1GAA | |
| SCHEMBL5013426 | 0.70 | RBP4 (0.40) | KCNN4DRD2DRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |