Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013361 | 0.89 | MEN1 (0.52) | MEN1KMT2AALDH1A1HSD17B10RAB9A | |
| SCHEMBL5063380 | 0.87 | RAB9A (0.67) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL27645188 | 0.83 | RAB9A (0.75) | MEN1KMT2AALDH1A1HSD17B10RAB9A | |
| SCHEMBL2091459 | 0.83 | SMN1; SMN2 (0.44) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL5015038 | 0.81 | RAB9A (0.50) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL5063385 | 0.75 | RAB9A (0.67) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL5015098 | 0.75 | SIGMAR1 (0.50) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL2096712 | 0.74 | SCD (0.50) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL2091149 | 0.74 | SMN1; SMN2 (0.68) | ALDH1A1HSD17B10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16226986 | 0.73 | ALDH1A1 (0.82) | MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |