⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241718 | 0.84 | — | — | |
| SCHEMBL23628544 | 0.82 | — | — | |
| SCHEMBL1438735 | 0.82 | — | — | |
| SCHEMBL5015183 | 0.80 | FABP4 (0.38) | — | |
| SCHEMBL5016486 | 0.76 | TOP1 (0.35) | — | |
| SCHEMBL5013036 | 0.76 | RAPGEF4 (0.30) | — | |
| SCHEMBL5015417 | 0.76 | KIF11 (0.35) | — | |
| SCHEMBL17651780 | 0.74 | HSD17B1 (0.38) | — | |
| SCHEMBL17651814 | 0.74 | HSD17B1 (0.38) | — | |
| SCHEMBL7050896 | 0.73 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417142-B2 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-02-09 | — | — | US | disclosed |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-06-09 | — | — | US | disclosed |