Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013649 | 0.84 | PCSK9 (0.47) | ATMC3AR1CTSSCTSKCTSL | |
| SCHEMBL5014055 | 0.82 | CTSK (0.43) | ATMACEMAPTCTSSCTSK | |
| SCHEMBL3586130 | 0.79 | KDM4A (0.40) | MEN1KMT2ANPSR1LMNAHTT | |
| SCHEMBL1196722 | 0.78 | ACE (0.45) | ACEC3AR1CTSSCTSKCTSL | |
| SCHEMBL800492 | 0.78 | KMT2A (0.49) | ATMC3AR1MAPTALDH1A1MEN1 | |
| SCHEMBL18764998 | 0.77 | HTT (0.50) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL18681306 | 0.76 | CA1 (0.40) | ATMMAPTCTSSCTSKCTSL | |
| SCHEMBL800480 | 0.76 | C3AR1 (0.49) | ATMC3AR1MAPTALDH1A1MEN1 | |
| SCHEMBL5014051 | 0.75 | ALDH1A1 (0.58) | ATMACEC3AR1MAPTCTSS | |
| SCHEMBL15214453 | 0.75 | C3AR1 (0.43) | ATMC3AR1MAPTCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321036-A | Treatment of diabetes, obesity and gastrointestinal disorders | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-14 | — | — | US | disclosed |