SCHEMBL5014092

SCHEMBL5014092

Cc1cc(C)c(OP(Oc2c(C)cc(C)cc2C)Oc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.38
ACHE P22303 2/20 0.35
MAPT P10636 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
CRHR1 P34998 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
GLA P06280 1/20 0.31
TSHR P16473 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10413826 0.85 RAPGEF4 (0.32) RAPGEF4ACHE
SCHEMBL10894088 0.83 ACHE (0.37) RAPGEF4ACHEMAPTLMNAKMT2A
SCHEMBL10886728 0.83 ACHE (0.37) RAPGEF4ACHEMAPTLMNAKMT2A
SCHEMBL5196643 0.80 SMN1; SMN2 (0.43) MAPTALDH1A1CYP1A2GLA
SCHEMBL11651622 0.79 RAPGEF4 (0.35) RAPGEF4ACHEMAPTALDH1A1KDM4E
SCHEMBL10413824 0.79 RAPGEF4 (0.35) RAPGEF4ACHEMAPTALDH1A1KDM4E
SCHEMBL8384673 0.79 RAPGEF4 (0.35) RAPGEF4ACHEMAPTALDH1A1KDM4E
SCHEMBL11056754 0.79 SMN1; SMN2 (0.42) MAPTALDH1A1CYP1A2GLATSHR
SCHEMBL14462077 0.74 L3MBTL1 (0.36) RAPGEF4ACHEMAPTALDH1A1KDM4E
SCHEMBL2603671 0.73 MAPT (0.35) MAPTALDH1A1KDM4ELMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858907-A Nickel phosphite catalysts MAXDEM, INCORPORATED (US) 1999-01-12 US claimed
WO-1996039455-A1 NICKEL PHOSPHITE CATALYSTS MAXDEM INCORPORATED (US) 1996-12-12 WO claimed
EP-0090524-B1 THERMAL OXIDATION STABILIZER COMPOSED OF PHOSPHITE DERIVATIVES OF AN ALCOHOL AND PPE MONOMER STILL BOTTOMS, AND PPE COMPOSITIONS CONTAINING SAID PHOSPHITES GENERAL ELECTRIC COMPANY (US) 1986-10-29 EP claimed
EP-0090524-A1 Thermal oxidation stabilizer composed of phosphite derivatives of an alcohol and PPE monomer still bottoms, and PPE compositions containing said phosphites GENERAL ELECTRIC COMPANY (US) 1983-10-05 EP claimed
WO-2026087408-A1 PROCESS FOR PREPARING ALPHA DELTA DI-CARBONYL DERIVATIVES FIRMENICH SA (CH) 2026-04-30 WO disclosed
EP-1947725-A2 Polymer electrolyte composition and fuel cell Sumitomo Chemical Company, Limited (JP) 2008-07-23 EP disclosed
EP-1289041-B1 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL CO (JP) 2008-03-12 EP disclosed
US-20060257706-A1 POLYMER ELECTROLYTE COMPOSITION AND FUEL CELL HIDAKA YASUAKI 2006-11-16 US disclosed
US-20030113605-A1 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-06-19 US disclosed
EP-1289041-A2 Polymer electrolyte composition and fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-05 EP disclosed
EP-0733671-B1 Polymethacrylate moulding matters stabilised against discolouration at thermal stress ROEHM GMBH (DE) 2001-06-13 EP disclosed
US-5919968-A OXIDIZING AN ORGANIC TRIVALENT PHOSPHORUS COMPOUND WITH AN AQUEOUS HYDROGEN PEROXIDE SOLUTION IN THE PRESENCE OF AN INORGANIC OR ORGANIC BASE AT A TEMPERATURE OF 0.DEGREE. C. TO 50.DEGREE. C. TO OBTAIN THE CORRESPONDING ORGANIC PENTAVALENT DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1999-07-06 US disclosed
EP-0844249-A1 Process for preparing organic pentavalent phosphorus compounds DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-05-27 EP disclosed
EP-0733671-A1 Polymethacrylate moulding matters stabilised against discolouration at thermal stress RÖHM GMBH (DE) 1996-09-25 EP disclosed
EP-0090524-B1 THERMAL OXIDATION STABILIZER COMPOSED OF PHOSPHITE DERIVATIVES OF AN ALCOHOL AND PPE MONOMER STILL BOTTOMS, AND PPE COMPOSITIONS CONTAINING SAID PHOSPHITES GENERAL ELECTRIC COMPANY (US) 1986-10-29 EP disclosed
EP-0090524-A1 Thermal oxidation stabilizer composed of phosphite derivatives of an alcohol and PPE monomer still bottoms, and PPE compositions containing said phosphites GENERAL ELECTRIC COMPANY (US) 1983-10-05 EP disclosed
US-4276233-A THERMAL STABILIZERS FOR POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1981-06-30 US disclosed