Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325298 | 0.90 | MAPT (0.31) | MAPTL3MBTL1 | |
| SCHEMBL2603177 | 0.89 | MAPT (0.30) | MAPTL3MBTL1 | |
| SCHEMBL14430030 | 0.88 | MAPT (0.32) | MAPTL3MBTL1LMNA | |
| SCHEMBL13767306 | 0.88 | — | — | |
| SCHEMBL14462077 | 0.85 | L3MBTL1 (0.36) | MAPTL3MBTL1TSHRNPC1RAB9A | |
| SCHEMBL12707930 | 0.81 | TSHR (0.38) | MAPTL3MBTL1LMNATSHRNPC1 | |
| SCHEMBL215848 | 0.80 | TSHR (0.46) | MAPTLMNATSHRNPC1RAB9A | |
| SCHEMBL27387712 | 0.80 | TSHR (0.46) | MAPTLMNATSHRNPC1RAB9A | |
| SCHEMBL29405565 | 0.80 | TSHR (0.46) | MAPTLMNATSHRNPC1RAB9A | |
| SCHEMBL12810471 | 0.79 | L3MBTL1 (0.42) | MAPTL3MBTL1LMNATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493405-B2 | Method for producing linear pentenenitrile | BASF SE (DE) | 2016-11-15 | — | — | US | disclosed |
| US-9493405-B2 | Method for producing linear pentenenitrile | BASF SE (DE) | 2016-11-15 | — | — | US | disclosed |
| US-20160168082-A1 | METHOD FOR PRODUCING LINEAR PENTENENITRILE | BASF SE (DE) | 2016-06-16 | — | — | US | disclosed |
| US-20160168082-A1 | METHOD FOR PRODUCING LINEAR PENTENENITRILE | BASF SE (DE) | 2016-06-16 | — | — | US | disclosed |
| EP-1472201-B1 | METHOD FOR THE SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC FLUIDS | BASF SE (DE) | 2014-08-13 | — | — | EP | disclosed |
| US-8410299-B2 | Method for producing linear pentenenitrile | BASF SE (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8410299-B2 | Method for producing linear pentenenitrile | BASF SE (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8373001-B2 | Method of producing dinitrile compounds | INVISTA NORTH AMERICA S.A R.L. (US) | 2013-02-12 | — | — | US | disclosed |
| US-8373001-B2 | Method of producing dinitrile compounds | INVISTA NORTH AMERICA S.A R.L. (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120178958-A1 | METHOD FOR PRODUCING LINEAR PENTENENITRILE | BASF SE* (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20080071105-A1 | NI(0) -CONTAINING CATALYST SYSTEM | BASF SE (DE) | 2008-03-20 | — | — | US | disclosed |
| US-7345006-B2 | Catalyst system containing Ni(0) for hydrocyanation | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345006-B2 | Catalyst system containing Ni(0) for hydrocyanation | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20070260086-A1 | Process for the Preparation of Dinitriles | INV NYLON CHEMICALS AMERICAS, LLC | 2007-11-08 | — | — | US | disclosed |
| US-20070260086-A1 | Process for the Preparation of Dinitriles | INV NYLON CHEMICALS AMERICAS, LLC | 2007-11-08 | — | — | US | disclosed |
| US-20070155978-A1 | Method for producing dinitriles | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
| US-20070155978-A1 | Method for producing dinitriles | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
| US-20070155979-A1 | Process for the hydrocyanation of unsaturated compounds | INV NYLON CHEMICALS AMERICAS, LLC | 2007-07-05 | — | — | US | disclosed |
| US-20070155979-A1 | Process for the hydrocyanation of unsaturated compounds | INV NYLON CHEMICALS AMERICAS, LLC | 2007-07-05 | — | — | US | disclosed |
| EP-1610893-B1 | SYSTEM SUITABLE FOR THE HYDROCYANATION OF OLEFINICALLY UNSATURATED COMPOUNDS | BASF AG (DE) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168082-A1 | METHOD FOR PRODUCING LINEAR PENTENENITRILE | METTL14, MSMO1, SPIN4 | MAPT 773/4885L3MBTL1 438/4885LMNA 1293/4885 |
| US-20070155979-A1 | Process for the hydrocyanation of unsaturated compounds | DDT, DBN1, HPD | MAPT 4863/4885L3MBTL1 1921/4885LMNA 847/4885 |
| US-20070155978-A1 | Method for producing dinitriles | ALKBH3, GLMN, GRHPR | MAPT 3643/4885L3MBTL1 2931/4885LMNA 2057/4885 |
| US-20120178958-A1 | METHOD FOR PRODUCING LINEAR PENTENENITRILE | METTL14, MBD2, ALKBH2 | MAPT 415/4885L3MBTL1 208/4885LMNA 1541/4885 |
| US-20070260086-A1 | Process for the Preparation of Dinitriles | DDT, NIT2, NOS2 | MAPT 3518/4885L3MBTL1 4457/4885LMNA 1728/4885 |
| US-20080071105-A1 | NI(0) -CONTAINING CATALYST SYSTEM | C1R, XDH, CBR1 | MAPT 4631/4885L3MBTL1 2732/4885LMNA 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.