Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651622 | 0.85 | RAPGEF4 (0.35) | RAPGEF4MAPTALDH1A1KDM4EGAA | |
| SCHEMBL5014092 | 0.79 | RAPGEF4 (0.38) | RAPGEF4MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10413824 | 0.75 | RAPGEF4 (0.35) | RAPGEF4MAPTALDH1A1KDM4EGAA | |
| SCHEMBL11287658 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAACHEKMT2A | |
| SCHEMBL15631886 | 0.75 | ALDH1A1 (0.39) | MAPTALDH1A1KDM4ELMNAACHE | |
| SCHEMBL8386751 | 0.73 | TDP1 (0.46) | MAPTALDH1A1KDM4EGAAACHE | |
| SCHEMBL1664850 | 0.73 | SMN1; SMN2 (0.50) | MAPTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL27274303 | 0.72 | ALDH1A1 (0.41) | MAPTALDH1A1ACHETP53TDP1 | |
| SCHEMBL10413826 | 0.71 | RAPGEF4 (0.32) | RAPGEF4ACHE | |
| SCHEMBL15364372 | 0.70 | RAPGEF4 (0.39) | RAPGEF4MAPTALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487343-B1 | Process for preparing a lithographic plate | FUJI PHOTO FILM CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |