Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15264534 | 0.77 | GSK3A (0.53) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL1929687 | 0.75 | ALOX12 (0.54) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL20997478 | 0.75 | ALOX12 (0.54) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL22728271 | 0.74 | KMT2A (0.51) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL5519242 | 0.74 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL6606867 | 0.74 | ALOX12 (0.53) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL21667263 | 0.73 | MEN1 (0.50) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL17639962 | 0.72 | KMT2A (0.80) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL9178601 | 0.72 | MEN1 (0.57) | MEN1KMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL9178596 | 0.72 | MEN1 (0.43) | MEN1KMT2AALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725641-A4 | — | — | 1996-09-04 | — | — | EP | claimed |
| EP-0725641-A1 | NOVEL ENZYME INHIBITORS, THEIR SYNTHESIS, AND METHODS FOR USE | El Kouni, Mahmoud H. (US) | 1996-08-14 | — | — | EP | claimed |
| WO-1995012400-A1 | NOVEL ENZYME INHIBITORS, THEIR SYNTHESIS, AND METHODS FOR USE | UAB RESEARCH FOUNDATION (US) | 1995-05-11 | — | — | WO | claimed |
| US-20180028535-A1 | 3-HYDROXYPYRIMIDINE-2,4-DIONE-5-CARBOXAMIDES AS POTENT INHIBITORS OF HIV | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-02-01 | — | — | US | disclosed |
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028535-A1 | 3-HYDROXYPYRIMIDINE-2,4-DIONE-5-CARBOXAMIDES AS POTENT INHIBITORS OF HIV | DPYD, IMPDH2, TYMP | MEN1 4800/4885KMT2A 255/4885ALDH1A1 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.