Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.56 |
| ▸ | HTR7 | P34969 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27661348 | 0.90 | SIGMAR1 (0.47) | TAAR1HTR7ACHEMAOAMAOB | |
| SCHEMBL609829 | 0.82 | TAAR1 (0.56) | TAAR1HTR7ACHEHTR1AHTR6 | |
| SCHEMBL5778962 | 0.81 | ALDH1A1 (0.48) | TAAR1HTR7ACHEMAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL28314198 | 0.81 | TAAR1 (0.54) | TAAR1HTR7ACHEHTR1AHTR6 | |
| SCHEMBL6525098 | 0.79 | MAOA (0.46) | MAOAMAOBALDH1A1 | |
| SCHEMBL910179 | 0.79 | MAOA (0.46) | MAOAMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL28313513 | 0.79 | TAAR1 (0.53) | TAAR1HTR7ACHEHTR1AHTR6 | |
| SCHEMBL7989985 | 0.77 | HRH3 (0.59) | TAAR1CHRNA7HRH3ALDH1A1 | |
| SCHEMBL5020713 | 0.77 | MAOA (0.56) | LTB4RLTB4R2MAOAMAOBALDH1A1 | |
| SCHEMBL10658892 | 0.77 | OPRM1 (0.53) | ACHEHTR1AMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |