SCHEMBL501769

SCHEMBL501769

Cc1cc(CO)cc(CO)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.48
PGK2 P07205 1/20 0.48
ACHE P22303 2/20 0.48
ALDH1A1 P00352 2/20 0.38
TPMT P51580 1/20 0.38
TSHR P16473 2/20 0.36
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
SELE P16581 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
C1S P09871 1/20 0.36
PRSS3 P35030 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CASP6 P55212 1/20 0.36
MAPT P10636 1/20 0.35
SHBG P04278 1/20 0.34
IDH1 O75874 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92965 0.94 ACHE (0.48) PGK1PGK2ACHEALDH1A1TPMT
Methoxymethane SCHEMBL27768340 0.92 PGK1 (0.43) PGK1PGK2ACHEALDH1A1TPMT
SCHEMBL25877374 0.92 SHBG (0.45) PGK1PGK2ACHEALDH1A1TPMT
SCHEMBL16952582 0.89 PGK1 (0.41) PGK1PGK2ACHEALDH1A1TPMT
SCHEMBL16956257 0.85 PGK1 (0.39) PGK1PGK2ACHEALDH1A1
Magnesium Chloride Anhydrous SCHEMBL28163486 0.84 ACHE (0.40) PGK1PGK2ACHEALDH1A1TPMT
SCHEMBL31139273 0.84 ACHE (0.67) PGK1PGK2ACHEALDH1A1SELL
SCHEMBL4848593 0.84 ACHE (0.67) PGK1PGK2ACHEALDH1A1SELL
SCHEMBL14882643 0.83 ESR1 (0.40) PGK1PGK2ACHEALDH1A1TPMT
SCHEMBL2904830 0.83 ACHE (0.41) PGK1PGK2ACHEALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO claimed
EP-2548739-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2015-12-16 EP claimed
EP-2548739-A2 Lithographic printing plate precursor Fujifilm Corporation (JP) 2013-01-23 EP claimed
WO-2025053791-A1 ONE-POT GRAFTING OF POLYMERS FROM ALCOHOLS AND BIOMASSES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-03-13 WO disclosed
CN-118085228-A Triazole curing material containing multiple hydrogen bonds and preparation method thereof 碳衡(重庆)生物质新材料有限公司 2024-05-28 CN disclosed
CN-114341103-B Aminoguanhydrazones as retrograde transport stabilizers useful in the treatment of neurological diseases 圣拉斐尔医院有限公司 2023-11-10 CN disclosed
CN-114341103-A Aminoguanidinohydrazones as reverse transporter stabilizers useful for the treatment of neurological disorders 圣拉斐尔医院有限公司 2022-04-12 CN disclosed
EP-3947344-A1 AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES Ospedale San Raffaele Srl (IT) 2022-02-09 EP disclosed
WO-2020201326-A1 AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES OSPEDALE SAN RAFFAELE SRL (IT) 2020-10-08 WO disclosed
US-20200277406-A1 BINDING AGENT ROCHE DIAGNOSTICS GMBH (DE) 2020-09-03 US disclosed
US-9890179-B2 Methods of preparing cytotoxic benzodiazepine derivatives IMMUNOGEN, INC. (US) 2018-02-13 US disclosed
WO-2007093621-A1 CYCLIC SULFONES USEFUL AS BACE INHIBITORS NOVARTIS AG (CH) 2007-08-23 WO disclosed
WO-2007085930-A1 CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE SANOFI-AVENTIS (FR) 2007-08-02 WO disclosed
EP-1813614-A1 Cytotoxic agents comprising new tomaymycin derivatives Sanofi-Aventis (FR) 2007-08-01 EP disclosed
US-6942955-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-13 US disclosed
US-20040229153-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-11-18 US disclosed
US-6699638-B2 ON A THERMAL CROSSLINKING LAYER A WATER SOLUBLE OVERCOAT LAYER, AND AT LEAST ONE OF THESE LAYERS CONTAINS A COMPOUND CAPABLE OF CONVERTING LIGHT INTO HEAT; EASY TO HANDLE AND CAUSES NO DEFECTS EVEN WHEN TOUCHED WITH FINGERS FUJI PHOTO FILM CO., LTD. (JP) 2004-03-02 US disclosed
US-6632580-B2 Hydrophilic support; recording using infrared radiation scanning radiation FUJI PHOTO FILM CO., LTD. (JP) 2003-10-14 US disclosed
EP-1160083-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-12-05 EP disclosed
US-20010031423-A1 On a thermal crosslinking layer a water soluble overcoat layer, and at least one of these layers contains a compound capable of converting light into heat; easy to handle and causes no defects even when touched with fingers FUJIFILM CORPORATION (JP) 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200277406-A1 BINDING AGENT SSB, APBA1, SHBG PGK1 4720/4885PGK2 4729/4885ACHE 2046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.