Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139273 | 1.00 | ACHE (0.67) | ACHEALDH1A1HCAR1PTGS2PGK1 | |
| SCHEMBL92965 | 0.84 | ACHE (0.48) | ACHEALDH1A1PGK1PGK2SELL | |
| SCHEMBL501769 | 0.84 | PGK1 (0.48) | ACHEALDH1A1PGK1PGK2SELL | |
| SCHEMBL10536338 | 0.83 | ESR1 (0.53) | ACHEALDH1A1HCAR1HSD17B1HSD17B2 | |
| SCHEMBL18458343 | 0.83 | ALDH1A1 (0.55) | ACHEALDH1A1HCAR1PTGS2PGK1 | |
| SCHEMBL29215628 | 0.82 | ALDH1A1 (0.60) | ACHEALDH1A1HCAR1PTGS2PGK1 | |
| SCHEMBL30899188 | 0.82 | ALDH1A1 (0.60) | ACHEALDH1A1HCAR1PTGS2PGK1 | |
| SCHEMBL351788 | 0.81 | ACHE (0.88) | ACHEPTGS2CYP3A4KDM4ECASP6 | |
| SCHEMBL248195 | 0.81 | ACHE (1.00) | ACHEALDH1A1PTGS2CYP3A4KDM4E | |
| SCHEMBL31200644 | 0.80 | ALDH1A1 (0.57) | ACHEALDH1A1HCAR1PTGS2PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342047-A1 | Cancerous Cell Growth Inhibiting Compounds | WISYS TECHNOLOGY FOUNDATION, INC. | 2017-11-30 | — | — | US | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| CN-103958473-B | Amide compound, composition and application thereof | ADVINUS THERAPEUTICS LTD. (IN) | 2016-11-30 | — | — | CN | disclosed |
| US-20150065464-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2015-03-05 | — | — | US | disclosed |
| US-8945508-B2 | Dendrimer compositions and methods of synthesis | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-02-03 | — | — | US | disclosed |
| EP-2758375-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | Advinus Therapeutics Limited (IN) | 2014-07-30 | — | — | EP | disclosed |
| CN-103958473-A | Amide compound, composition and application thereof | ADVINUS THERAPEUTICS LTD | 2014-07-30 | — | — | CN | disclosed |
| WO-2013042139-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-03-28 | — | — | WO | disclosed |
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-7429669-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-20070293669-A1 | Invertible amphiphilic polymers | UNIVERSITY OF MASSACHUSETTS | 2007-12-20 | — | — | US | disclosed |
| CN-101070316-A | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARMA GMBH (DE) | 2007-11-14 | — | — | CN | disclosed |
| CN-1331862-C | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARAMCEUTICALS PRODUC (DE) | 2007-08-15 | — | — | CN | disclosed |
| US-6635655-B1 | Agonists or antagonists of peroxisome proliferator-activated receptors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-10-21 | — | — | US | disclosed |
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| WO-1989004305-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342047-A1 | Cancerous Cell Growth Inhibiting Compounds | TYR, MKI67, MC1R | ACHE 3485/4885ALDH1A1 113/4885HCAR1 1654/4885 |
| US-20070293669-A1 | Invertible amphiphilic polymers | PHOSPHO1, INF2, AQP1 | ACHE 1807/4885ALDH1A1 4784/4885HCAR1 3298/4885 |
| US-20150065464-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF | FAAH, FAAH2, TPH1 | ACHE 9/4885ALDH1A1 2023/4885HCAR1 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.