Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731356 | 0.92 | ALOX5 (0.69) | ALOX5MAOBMAOAHIF1ANR1H4 | |
| SCHEMBL10638674 | 0.86 | ALOX5 (0.61) | ALOX5MAOBMAOANR1H4ALDH1A1 | |
| SCHEMBL22992559 | 0.78 | ALOX5 (0.57) | ALOX5MAOBMAOAALDH1A1KMT2A | |
| SCHEMBL4707088 | 0.77 | MAOB (0.58) | ALOX5MAOBMAOAALDH1A1KMT2A | |
| SCHEMBL6092993 | 0.76 | ALOX5 (0.76) | ALOX5MAOBMAOAALDH1A1KMT2A | |
| SCHEMBL3452161 | 0.76 | MAOB (0.52) | ALOX5MAOBMAOAALDH1A1KMT2A | |
| SCHEMBL13213562 | 0.74 | MAOB (0.54) | ALOX5MAOBMAOAALDH1A1CA2 | |
| SCHEMBL9729874 | 0.73 | ALOX5 (1.00) | ALOX5MAOBMAOAALDH1A1 | |
| SCHEMBL949460 | 0.72 | MAOB (0.51) | ALOX5MAOBMAOAALDH1A1CA2 | |
| SCHEMBL17594260 | 0.72 | NR1H4 (0.44) | ALOX5MAOBNR1H4ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146896-A1 | BICYCLIC-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS | PARION SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| US-7446127-B2 | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders | SK HOLDINGS CO, LTD. (KR) | 2008-11-04 | — | — | US | disclosed |
| US-7446127-B2 | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders | SK HOLDINGS CO, LTD. (KR) | 2008-11-04 | — | — | US | disclosed |
| US-7446127-B2 | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders | SK HOLDINGS CO, LTD. (KR) | 2008-11-04 | — | — | US | disclosed |
| EP-1660490-A1 | CHROMAN CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS | SK Corporation (KR) | 2006-05-31 | — | — | EP | disclosed |
| US-20050107371-A1 | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2005-05-19 | — | — | US | disclosed |
| WO-2005021540-A1 | CHROMAN CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS | SK CORPORATION (KR) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107371-A1 | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders | GPR119, CEL, ACACA | ALOX5 628/4885MAOB 1329/4885MAOA 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.