SCHEMBL501878

SCHEMBL501878

CC1OC(=O)C=C1N(Cc1ccc(Cl)nc1)CC(F)F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728026 1.00 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AATMLMNA
SCHEMBL28773340 0.85 ALDH1A1 (0.35) ALDH1A1LMNAL3MBTL1PSEN1PSEN2
SCHEMBL2891247 0.81 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ALMNAL3MBTL1
SCHEMBL14949164 0.78 ALDH1A1 (0.33) ALDH1A1MEN1KMT2AATM
SCHEMBL21462548 0.78 ALDH1A1 (0.34) ALDH1A1LMNAL3MBTL1PSEN1PSEN2
SCHEMBL502277 0.78 ALDH1A1 (0.34) ALDH1A1LMNAL3MBTL1PSEN1PSEN2
SCHEMBL502278 0.78 ALDH1A1 (0.34) ALDH1A1LMNAL3MBTL1PSEN1PSEN2
SCHEMBL123283 0.75 KDM1A (0.32) ALDH1A1MEN1KMT2AATMPSEN1
SCHEMBL29394548 0.75 KDM1A (0.32) ALDH1A1MEN1KMT2AATMPSEN1
SCHEMBL231409 0.74 MEN1 (0.33) ALDH1A1MEN1KMT2AATMPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP claimed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US claimed
WO-2021069628-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO claimed
EP-3772943-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE Bayer Aktiengesellschaft (DE) 2021-02-17 EP claimed
WO-2019197635-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO claimed
EP-4275493-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS Bayer Aktiengesellschaft (DE) 2023-11-15 EP disclosed
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
WO-2021069628-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO disclosed
EP-3772943-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE Bayer Aktiengesellschaft (DE) 2021-02-17 EP disclosed
WO-2019197635-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING PROPYLENE CARBONATE BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO disclosed
EP-2004635-B1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER IP GMBH (DE) 2015-09-23 EP disclosed
EP-2004635-B1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER IP GMBH (DE) 2015-09-23 EP disclosed
EP-2327304-A1 Use of substituted enaminocarbonyl compounds for combating animal pests Bayer CropScience AG (DE) 2011-06-01 EP disclosed
EP-2327304-A1 Use of substituted enaminocarbonyl compounds for combating animal pests Bayer CropScience AG (DE) 2011-06-01 EP disclosed
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG 2009-10-08 US disclosed
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG 2009-10-08 US disclosed
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG 2009-10-08 US disclosed
EP-2004635-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS Bayer CropScience AG (DE) 2008-12-24 EP disclosed
WO-2007115644-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed
WO-2007115644-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230068010-A1 FORMULATION OF INSECTICIDAL MIXTURES COMPRISING GLYCOL ETHER SOLVENTS SGMS2, SGMS1, CYP51A1 ALDH1A1 3100/4885MEN1 3305/4885KMT2A 3776/4885
US-20090253749-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS DDT, NPEPPS, L3MBTL4 ALDH1A1 4014/4885MEN1 2562/4885KMT2A 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.