Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446612 | 0.90 | ALDH1A1 (0.43) | DGAT1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL3445760 | 0.89 | ALDH1A1 (0.40) | DGAT1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL461296 | 0.89 | ALDH1A1 (0.40) | DGAT1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL16446807 | 0.84 | SRC (0.37) | DGAT1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL19519484 | 0.84 | SRC (0.38) | DGAT1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL13035551 | 0.83 | ALDH1A1 (0.37) | SRCALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL17796084 | 0.83 | SRC (0.34) | DGAT1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL19519626 | 0.83 | SRC (0.34) | DGAT1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL18053742 | 0.82 | DGAT1 (0.38) | DGAT1ALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL13073687 | 0.82 | ALDH1A1 (0.35) | ALDH1A1HPGDHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053999-A1 | Tricyclic Benzoxaborole Compounds and Uses Thereof | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2021-02-25 | — | — | US | disclosed |
| US-20180037595-A1 | BENZOXABOROLE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-02-08 | — | — | US | disclosed |
| US-20160251380-A1 | TRICYCLIC BENZOXABOROLE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-09-01 | — | — | US | disclosed |
| US-20150133402-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, LLC | 2015-05-14 | — | — | US | disclosed |
| US-8895534-B2 | Boron containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20120115813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-20100292504-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-7816344-B2 | oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics | ANACOR PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090227541-A1 | oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics | ANACOR PHARMACEUTICALS, INC. (US) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053999-A1 | Tricyclic Benzoxaborole Compounds and Uses Thereof | CBX2, BRD4, BRD3 | DGAT1 3194/4885CCNB2 66/4885CDK1 814/4885 |
| US-20160251380-A1 | TRICYCLIC BENZOXABOROLE COMPOUNDS AND USES THEREOF | CBX2, BRD4, BRD3 | DGAT1 3194/4885CCNB2 66/4885CDK1 814/4885 |
| US-20100292504-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BCL6 | DGAT1 3618/4885CCNB2 1029/4885CDK1 1936/4885 |
| US-20150133402-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BCL6 | DGAT1 3618/4885CCNB2 1029/4885CDK1 1936/4885 |
| US-20120115813-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BTD, BROX | DGAT1 3696/4885CCNB2 500/4885CDK1 2431/4885 |
| US-20180037595-A1 | BENZOXABOROLE COMPOUNDS AND USES THEREOF | BRD3, BRPF3, BRD4 | DGAT1 3263/4885CCNB2 208/4885CDK1 1564/4885 |
| US-20090227541-A1 | oxaboroles such as 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol, useful for treating bacterial infections; microbiocides; antibiotics | OXA1L, TLR1, OXER1 | DGAT1 1285/4885CCNB2 3865/4885CDK1 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.