Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 4/20 | 0.67 |
| ▸ | FLT4 | P35916 | 4/20 | 0.67 |
| ▸ | KDR | P35968 | 4/20 | 0.67 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343103 | 0.84 | TP53 (0.52) | FLT1FLT4KDRKMT2AMEN1 | |
| SCHEMBL9468104 | 0.82 | CA1 (0.64) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL9483252 | 0.82 | KMT2A (0.58) | FLT1FLT4KDRKMT2AMEN1 | |
| SCHEMBL9466896 | 0.81 | CA12 (0.56) | FLT1FLT4KDRPCTPKMT2A | |
| SCHEMBL9467651 | 0.81 | ALDH1A1 (0.54) | KMT2AMEN1MAPTKDM4EPKM | |
| SCHEMBL28113465 | 0.80 | BDKRB1 (0.63) | FLT1FLT4KDRPRMT1KMT2A | |
| SCHEMBL9467745 | 0.80 | LMNA (0.54) | FLT1FLT4KDRKMT2AMEN1 | |
| SCHEMBL9484009 | 0.80 | ALDH1A1 (0.56) | FLT1FLT4KDRKMT2AMEN1 | |
| SCHEMBL9467796 | 0.80 | HDAC3 (0.60) | FLT1FLT4KDRKMT2AMEN1 | |
| SCHEMBL9468055 | 0.79 | RAB9A (0.64) | KMT2AMEN1MAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |