Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020769 | 0.87 | HDAC1 (0.78) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL23088918 | 0.87 | CA2 (0.56) | HDAC1CA1CA2CA9CA12 | |
| SCHEMBL5020621 | 0.86 | HDAC1 (1.00) | HDAC1HDAC4HDAC8CA1CA2 | |
| SCHEMBL5020762 | 0.86 | HDAC1 (0.76) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL5020765 | 0.84 | HDAC1 (0.79) | HDAC1HDAC4HDAC8CA1CA2 | |
| SCHEMBL5020761 | 0.84 | HDAC1 (0.79) | HDAC1HDAC4HDAC8CA1CA2 | |
| SCHEMBL5020774 | 0.84 | HDAC1 (0.77) | HDAC1HDAC4HDAC8HDAC3HDAC7 | |
| SCHEMBL14629569 | 0.83 | HDAC1 (0.76) | HDAC1HDAC4HDAC8CA1CA2 | |
| SCHEMBL5020752 | 0.83 | HDAC1 (0.77) | HDAC1HDAC4HDAC8CA1CA2 | |
| SCHEMBL5020744 | 0.81 | PKM (0.58) | HDAC1HDAC4HDAC8HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43343-E1 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-05-01 | — | — | US | disclosed |