Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92947 | 0.92 | CA2 (0.33) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL12275897 | 0.89 | SMN1; SMN2 (0.36) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL3735742 | 0.88 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL11129630 | 0.85 | SMN1; SMN2 (0.31) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL22435 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP2C19GSK3AGSK3BKMT2A | |
| SCHEMBL15994679 | 0.79 | CA2 (0.37) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL92976 | 0.79 | CA2 (0.37) | ALDH1A1KMT2AATMLMNAMEN1 | |
| SCHEMBL8528682 | 0.79 | MGLL (0.34) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL3186902 | 0.79 | MGLL (0.34) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL5316357 | 0.78 | KMT2A (0.33) | ALDH1A1CYP1A2CYP2C19HPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227555-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-07-24 | — | — | US | disclosed |
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |