Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.35 |
| ▸ | CDK9 | P50750 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640341 | 0.81 | MAPT (0.35) | MAPTTSHRCCNT1CDK9HTT | |
| SCHEMBL23801890 | 0.72 | NAMPT (0.38) | MAPTTSHRCCNT1CDK9 | |
| SCHEMBL16404760 | 0.70 | — | — | |
| SCHEMBL5051561 | 0.69 | MAPT (0.42) | MAPTTSHRHTTPPARDEGFR | |
| SCHEMBL26738625 | 0.69 | HMGCR (0.38) | MAPTTSHRHTTEGFRHMGCR | |
| SCHEMBL5052076 | 0.68 | TSHR (0.39) | MAPTTSHRHTTPPARDEGFR | |
| SCHEMBL2668814 | 0.68 | TSHR (0.35) | MAPTTSHRHTTPPARD | |
| SCHEMBL1767774 | 0.68 | PPARD (0.39) | TSHRCCNT1CDK9PPARD | |
| SCHEMBL5010543 | 0.67 | PGK1 (0.52) | MAPTTSHRCCNT1CDK9HTT | |
| SCHEMBL992724 | 0.67 | ALDH1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |