SCHEMBL502220

SCHEMBL502220

COC(=O)C1=CC(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 2/20 0.38
MEN1 O00255 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
IDO1 P14902 1/20 0.38
PTPN1 P18031 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.36
CYP1A2 P05177 1/20 0.36
PIM1 P11309 1/20 0.36
KDM4E B2RXH2 2/20 0.35
GAA P10253 2/20 0.35
GLA P06280 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HTT P42858 1/20 0.35
PADI4 Q9UM07 1/20 0.35
TSHR P16473 1/20 0.34
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2027730 0.79 ALDH1A1 (0.43) MAPTALDH1A1KMT2APOLBMEN1
SCHEMBL11199989 0.77 IDO1 (0.34) MAPTALDH1A1IDO1PTPN1CYP1A2
SCHEMBL28229004 0.76 KMT2A (0.31) KMT2A
SCHEMBL347103 0.73 LDHA (0.32)
SCHEMBL11880209 0.71
SCHEMBL6022461 0.71
SCHEMBL3794407 0.71 CASP3 (0.35) MAPTALDH1A1KMT2AMEN1KDM4E
SCHEMBL1286136 0.71 KDM4E (0.33) MAPTALDH1A1POLBTDP1CYP1A2
SCHEMBL5669047 0.71 MGLL (0.32)
SCHEMBL8586498 0.71 CYP3A4 (0.46) MAPTALDH1A1KMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681935-A2 SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS Evorion Biotechnologies GmbH (DE) 2020-07-22 EP claimed
CN-107501378-B A kind of glycocholic acid polyethyleneglycol derivative and preparation method thereof 湖南华腾制药有限公司 2019-05-14 CN claimed
WO-2019048714-A2 SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS EVORION BIOTECHNOLOGIES GMBH (DE) 2019-03-14 WO claimed
CN-107501378-A A kind of glycocholic acid polyethyleneglycol derivative and preparation method thereof 湖南华腾制药有限公司 2017-12-22 CN claimed
CN-107033277-A Side chain liquid crystalline polymer of ternary polymerization and preparation method thereof 上海交通大学 2017-08-11 CN claimed
CN-104871118-B Basement membrane includes the laminar structure and display device of the basement membrane LG化学株式会社 2017-07-18 CN claimed
JP-4490290-B2 2010-06-23 JP claimed
WO-2009011486-A1 A NEW PREPARING METHOD OF METHOXYPOLYETHYLENEGLYCOL ETHYLMALEIMIDE ID BIOCHEM, INC. (KR) 2009-01-22 WO claimed
JP-2006512445-A 2006-04-13 JP claimed
EP-1578842-A2 HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS Nektar Therapeutics Al, Corporation (US) 2005-09-28 EP claimed
WO-2004060965-A2 HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS NEKTAR THERAPEUTICS AL, CORPORATION (US) 2004-07-22 WO claimed
WO-2023118892-A1 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-06-29 WO disclosed
WO-2023118891-A1 METHOD OF CHARACTERISING POLYPEPTIDES USING A NANOPORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-06-29 WO disclosed
WO-2023118961-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF INTOCELL, INC. (KR) 2023-06-29 WO disclosed
EP-4183773-A1 ZWITTERIONIC REAGENTS Siemens Healthcare Diagnostics Inc. (US) 2023-05-24 EP disclosed
US-5242680-A Diagnostic and therapeutic MERCK & CO., INC. (US) 1993-09-07 US disclosed
EP-0524722-A1 Thiol-reactive maleimido-based radiolabeling reagents MERCK & CO. INC. (US) 1993-01-27 EP disclosed
WO-1992011029-A1 SUPPRESSION OF IMMUNE RESPONSES WITH OLIGOMERIC FORMS OF ANTIGEN OF CONTROLLED CHEMISTRY THE JOHNS HOPKINS UNIVERSITY (US) 1992-07-09 WO disclosed
US-4536391-A REACTING A PLASMIN HEAVY CHAIN WITH UROKINASE IN THE PRESENCE OF A COUPLING AGENT OTSUKA PHARMACEUTICAL CO. (JP) 1985-08-20 US disclosed
EP-0109653-A2 Process for preparing urokinase complex OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-05-30 EP disclosed