Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.66 |
| ▸ | HTR1A | P08908 | 5/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | EDNRA | P25101 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281471 | 0.84 | ADRA1D (0.79) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL17471518 | 0.83 | ADRA1D (0.80) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL4911405 | 0.83 | ADRA1D (0.80) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| Water SCHEMBL6231086 | 0.81 | ADRA1D (0.77) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL9548029 | 0.81 | ADRA1D (0.83) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| Tamsulosin SCHEMBL9121593 | 0.80 | ADRA1A (0.96) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| Tamsulosin SCHEMBL53998 | 0.80 | ADRA1A (1.00) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| Hydrochloric Acid SCHEMBL9548066 | 0.80 | ADRA1D (0.81) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| Tamsulosin SCHEMBL34378 | 0.80 | ADRA1A (1.00) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| Tamsulosin SCHEMBL30465862 | 0.80 | ADRA1A (1.00) | ADRA1DADRA1AADRA1BHTR1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088838-A1 | METHODS FOR MAINTAINING EFFECTIVE PLASMA CONCENTRATIONS OF A PHARMACEUTICAL | ASTELLAS PHARMA INC. (JP) | 2012-04-12 | — | — | US | disclosed |
| US-8128958-B2 | Sustained release pharmaceutical composition | ASTELLAS PHARMA INC. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20050100603-A1 | Sustained release pharmaceutical composition | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088838-A1 | METHODS FOR MAINTAINING EFFECTIVE PLASMA CONCENTRATIONS OF A PHARMACEUTICAL | ADRB1, NPSR1, ADRA1B | ADRA1D 17/4885ADRA1A 5/4885ADRA1B 3/4885 |
| US-20050100603-A1 | Sustained release pharmaceutical composition | ADRB1, ADRA1B, ADRB2 | ADRA1D 5/4885ADRA1A 4/4885ADRA1B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.