Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862119 | 0.81 | KCNA5 (0.53) | KDM1AKDM4ELTA4HALDH1A1KMT2A | |
| SCHEMBL3866660 | 0.74 | CACNA2D1 (0.53) | KDM1AKDM4ELTA4HHTR7 | |
| SCHEMBL4177226 | 0.73 | LTA4H (0.58) | KDM1AKDM4ELTA4HALDH1A1KMT2A | |
| SCHEMBL3862213 | 0.72 | KMT2A (0.52) | KMT2AGAA | |
| SCHEMBL3862105 | 0.72 | HTR7 (0.43) | KDM1AALDH1A1KMT2AHTR7LMNA | |
| SCHEMBL5023966 | 0.71 | KCNH2 (0.49) | KDM4EALDH1A1LMNA | |
| SCHEMBL4173098 | 0.71 | LTA4H (0.59) | KDM1AKDM4ELTA4HALDH1A1 | |
| SCHEMBL4182228 | 0.70 | LTA4H (0.55) | KDM4ELTA4HALDH1A1KMT2AHTR7 | |
| SCHEMBL13698799 | 0.69 | KDM4E (0.69) | KDM4ELTA4HALDH1A1KMT2ALMNA | |
| SCHEMBL2157515 | 0.69 | EPHX2 (0.44) | KDM1ALTA4HKMT2AHTR7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871372-A1 | COMBINATION THERAPY COMPRISING AN N-TYPE CALCIUM CHANNEL BLOCKER FOR THE ALLEVIATION OF PAIN | Neuromed Pharmaceuticals, Ltd. (CA) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006105670-A1 | COMBINATION THERAPY COMPRISING AN N-TYPE CALCIUM CHANNEL BLOCKER FOR THE ALLEVIATION OF PAIN | NEUROMED PHARMACEUTICALS LTD. (CA) | 2006-10-12 | — | — | WO | disclosed |