SCHEMBL5025484

SCHEMBL5025484

Cc1cc2c(cc1C)-c1ccccc1C2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
PGR P06401 2/20 0.49
SRD5A2 P31213 1/20 0.47
MAOA P21397 2/20 0.46
CYP1A2 P05177 4/20 0.46
HTR2C P28335 2/20 0.46
HTR2B P41595 2/20 0.46
ADRA2A P08913 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
CYP3A4 P08684 3/20 0.44
TSHR P16473 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904089 0.84 MAOA (0.67) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL5016641 0.84 SMN1; SMN2 (0.64) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL30912172 0.84 SMN1; SMN2 (0.64) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL5058433 0.84 SMN1; SMN2 (0.64) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL18582934 0.84 SMN1; SMN2 (0.64) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL10917281 0.83 HTT (0.39) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL29633536 0.83 HTT (0.39) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL547186 0.83 ALDH1A1 (0.53) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
SCHEMBL30543060 0.82 NPC1 (0.48) ALDH1A1MAPTHPGDSMN1; SMN2NPC1
Fluorene SCHEMBL28561231 0.81 MAOA (0.54) ALDH1A1MAPTHPGDSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220145161-A1 GREEN COMPOSITIONS FOR USE IN DOWNHOLE AND INDUSTRIAL APPLICATIONS DELTA-ENERGY GROUP, LLC (US) 2022-05-12 US disclosed
CN-112105654-A Curable resin mixture, curable resin composition, and cured product thereof 日本化药株式会社 2020-12-18 CN disclosed
WO-2020031935-A1 CURABLE RESIN MIXTURE, CURABLE RESIN COMPOSITION, AND CURED PRODUCT 日本化薬株式会社 2020-02-13 WO disclosed
EP-2939288-B1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2019-11-06 EP disclosed
CN-103868763-A Method for collecting gas-state organic pollutants and implementation device thereof UNIV TONGJI 2014-06-18 CN disclosed
WO-2008051382-A2 METHOD OF MAKING A SOLVENT FROM RUBBER TIRES NATURAL RESOURCE RECOVERY, INC. (US) 2008-05-02 WO disclosed
US-20080096787-A1 from waste tires comprising heating tire particles in an enclosures to generate hydrocarbon vapors rich in limonene and naphthalene, and carbon black solids NATURAL RESOURCE RECOVERY, INC. 2008-04-24 US disclosed
WO-2007079133-A2 SYSTEM AND METHOD FOR RECYCLING WASTE INTO ENERGY NATURAL RESOURCE RECOVERY, INC. (US) 2007-07-12 WO disclosed
EP-1120389-B1 Preparation process of fluorenes JFE CHEMICAL CORP (JP) 2003-11-26 EP disclosed
US-6344585-B2 DEHYDROGENATION OF THE CORRESPONDING TETRAHYDROFLUORENECOMPOUND ADCHEMCO CORPORATION (JP) 2002-02-05 US disclosed
US-20010011144-A1 Preparation process of fluorenes ADCHEMCO CORPORATION (JP) 2001-08-02 US disclosed
EP-1120389-A1 Preparation process of fluorenes Adchemco Corporation (JP) 2001-08-01 EP disclosed
US-4599445-A Process for benzophenone tetracarboxylic acid THE DOW CHEMICAL COMPANY (US) 1986-07-08 US disclosed
US-4562271-A Preparation of 3-alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1985-12-31 US disclosed
US-4485247-A 3-Alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1984-11-27 US disclosed
EP-0125342-A1 Process for preparation of aromatic polycarboxylic acids and intermediates therefor THE UPJOHN COMPANY (US) 1984-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010011144-A1 Preparation process of fluorenes AFF1, NAF1, RER1 ALDH1A1 563/4885MAPT 4536/4885HPGD 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.